Dr. Yaacov Rozenman, Head of Shaarei Tzedek’s Ophthalmology Department Background A cataract pathology causes the partial or entire lens clouding inside the eye, resulting in blurred or distorted vision. Cataract retrieval surgery is one of the ...

  Category Life Sciences and Biotechnology    Keywords Cathespin, Molecular Imaging, Cancer, CT, Computed Tomography, Current development stage TRL3 - Hypothesis testing and initial POC demonstrated in-vivo Application X-ray computed ...

  Our Innovation   Based on a provocative working hypothesis, we most probably identified the molecular origin of insulin resistance (IR). Systemic IR is induced via post-translational modification (PTM) of liver key regulatory proteins. We ...

Dr. Sharon Merims, Hadassah Medical Center   Background Many of the anti-neoplastic tyrosine kinase inhibitors are associated with prominent and sometimes dose-limiting dermatologic complications. Of severe clinical implication are the specific ...

Background Natural killer (NK) cells are innate effector lymphocytes that efficiently kill tumor cells without prior stimulation. NK are crucial first responders to tumor transformation and viral, bacterial, or fungal infections. They are also ...

Background The current commercial photo-initiators are unsuitable for radical-polymerization of adhesive coatings and 2&3D printing due to their poor water solubility, low efficiency and restricted suitability to the emerging LED ...

Our Innovation An interactive web-based map based on innovative digital-mapping and information visualization technologies designed to explore and experience Jewish cultures in their historical development from a perspective of time and ...

Background Emulsification in aqueous media is not effective for the encapsulation of hydrophilic drugs. Peptides and proteins may deteriorate when exposed to aqueous-organic interfaces Neuropeptides are potent CNS neuromodulators and have many ...

Category Life Sciences and Bio Technology    Keywords Chemotherapy, Drug resistance * The project is conducted in collaboration with Memorial Sloan-Kettering Cancer Center. Application Cells with multidrug resistance (MDR) due to aberrant ...

      Our Innovation We found and patented that approved drugs enhance the expression of NKp30 ligand. The upregulation is persistent and does not affect cell viability. We suggest to use this new modality as a combination therapy to improve ...

Application Middleboxes play a major role in Software Defined Networks (SDN) as forwarding compressed packets is not enough to meet operators demands in terms of security, QoS/QoE provisioning and load balancing. In current systems, Deep Packet ...

Our Innovation   The finding by HUJI researchers uncovers a novel structure of an outer mitochondrial membrane [Fe-S] protein (mitoNEET) determined by X-ray crystallography (Fig 1)  MitoNEET is an outer mitochondrial membrane protein that ...

  Vibrant, Efficient, Low-Cost Emitters:   Background Perovskite nanoparticles are revolutionizing display technologies by down-converting some of the light from the blue LED backlight to narrow-band red and green components which results in ...

  Background Many important biochemical compounds and drugs of natural origin contain spirofuranone ring structures (these structures exist among carbohydrates, terpenoids, vitamins, alkaloids, glycosides and antibiotics). All derived from a ...

  Background        Very small tumors (<5mm) in gastrointestinal GI tract can hardly be detected by external means (CT, MRI, etc.) or ultrasound endoscopic examination. Stomach and liver cancers as well as pancreas are deadliest diseases ...

Background: Autism spectrum disorder (ASD) is one of the fastest growing developmental disability in the United States, represents a group of neurodevelopmental disorders characterized by impaired social interaction and communication as well as ...

  Background Oxazine, Azaspirone, Quinolines, Quinolinone, and Quinolinol structures are frequently observed as scaffold segments in various biochemical compounds. These architectures have been identified as building blocks of a numerous ...

  Background Methylene lactone structures are frequently observed as scaffold segments of various biochemical compounds. These architectures have been identified as building blocks of numerous terpenoids, as well as other families of diverse ...

Background As for today, an oral treatment to metastasis therapy is still an unmet challenge. We discovered a new approach to treat metastatic disease in that was verified in several preclinical models. Our Innovation A new approach to treat ...

  Category Food & Nutrition, Computer-aided drug discovery   Keywords Bitter, Sweet, Machine Learning, Chemical features Current development stage TRL7  System prototype demonstration Application Basic taste qualities like sweet, ...