Projects related to 47-2020-14924

BackgroundToday’s current method of covering up scars, skin blemishes and topical wounds is limited to makeup or costly skin grafting for major repairs. While makeup is an affordable option, it is not a viable solution since it requires daily ...

Harnesses the self-assembly capabilities of cellulose binding domain (CBD)   Background There is a great demand in the field of nano-biotechnology and material science for a reliable, highly stable building block that can self-assemble to form ...

Background Cement & Gypsum require a lot of energy for production, consume large areas of land and are hard to recycle. There is a global need for new environment-friendly, low cost materials for construction. Our Innovation Utilizing ...

  Categories Superactive High Afinity Leptin antagonist, mutein, multiple sclerosis, inflammatory bowel syndrome, rheumatoid arthritis, fibrosis, cardiovascular disease, CKD Cachexia, Osteoarthritis Development Stage (1) In vivo tests in ...

  Background DNA mutations in mitochondrial proteins/enzymes (nuclear encoded) that may lead to disease are present in approximately 1 in 8,000 individuals. Any treatment for mitochondrial diseases must be capable of targeting and crossing the ...

  Background It was recently shown that enhanced expression of NAF-1, is associated with different cancers, including breast, prostate, gastric, cervical, liver, and laryngeal. Silencing of NAF-1 expression in breast, or gastric, cancer cells ...

  Our Innovation   Based on a provocative working hypothesis, we most probably identified the molecular origin of insulin resistance (IR). Systemic IR is induced via post-translational modification (PTM) of liver key regulatory proteins. We ...

Background Emulsification in aqueous media is not effective for the encapsulation of hydrophilic drugs. Peptides and proteins may deteriorate when exposed to aqueous-organic interfaces Neuropeptides are potent CNS neuromodulators and have many ...

Background With continuous increase in the elderly population, many age-related health problems have become a major healthcare issue. Attenuating deleterious age-related processes taking place in multiple organs is highly desirable. Our ...

Fills the gap between crystallography and optical imaging    Background Information about macromolecules is encoded in their shape and the way they are assembled. X-ray scattering methods are important tools for investigating the structure and ...

Background Peptides are key players in a variety of physiological and pathological processes and play very important roles in modulating various cell functions. One of the most important challenges developing peptide drugs is the lack of ...

Background Parkinson’s Disease (PD) is a progressive neurodegenerative disease caused by the loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). As the disease progresses the number of dopaminergic neurons decreases. ...

Protein Secretion is a fundamental aspect in production of therapeutic proteins in eukaryotic cells. Most therapeutic proteins are produced as secreted proteins in mammalian cells such as CHO and HEK293.  An essential milestone in the production ...

Category Agriculture, Food& Nutrition,  Life Science & Biotechnology Keywords Protein expression, Plant expression, biosimilar , Food, Nutrition, Functional Food, Addatives, Peptides, Protein Current development stage General list: ...

  Novel Humanin Analogs for Treatment of Neuroprotection and Myoprotection Category Life Sciences and Biotechnology    Keywords Neuroprotection, Myoprotection, Stroke, Mitochondria dysfunction  ApplicationMitochondrial-derived peptides ...

 Application Uveitis is inflammation inside the eye, specifically affecting one or more of the three parts of the eye that make up the uvea. It is induced by eye infiltration of T lymphocytes capable of recognizing retinal antigens. Uveitis is ...