| Technology Name | Briefcase | Lead Researcher |
|---|---|---|
Category
LifeSciences and BioTechnology
Keywords
Natural compounds, Synthetic compounds, Neurodegenerative disorders
Current development stage
For Pharmaceutical development: TRL4 - POC & Safety of candidate drug formulation is ... More | Tsvelikhovsky Dmitry | |
Our Innovation
Based on a provocative working hypothesis, we most probably identified the molecular origin of insulin resistance (IR). Systemic IR is induced via post-translational modification (PTM) of liver key regulatory proteins. We ... More | Ben-Sasson Shmuel | |
Background
Oxazine, Azaspirone, Quinolines, Quinolinone, and Quinolinol structures are frequently observed as scaffold segments in various biochemical compounds. These architectures have been identified as building blocks of a numerous ... More | Tsvelikhovsky Dmitry | |
Background
Methylene lactone structures are frequently observed as scaffold segments of various biochemical compounds.
These architectures have been identified as building blocks of numerous terpenoids, as well as other families of diverse ... More | Tsvelikhovsky Dmitry | |
Background
As for today, an oral treatment to metastasis therapy is still an unmet challenge. We discovered a new approach to treat metastatic disease in that was verified in several preclinical models.
Our Innovation
A new approach to treat ... More | Reich Reuven | |
Background
Malaria is caused by unicellular Plasmodium parasites which are transmitted by the bite of mosquitoes. Although several medicines are available for prophylaxis and treatment of acute infection, their application is severely hampered ... More | Dzikowski Ron | |
Additional information will be provided upon request
More | Domb Abraham | |
Category
LifeSciences and BioTechnology
Keywords
Natural compounds, Synthetic compounds, Neurodegenerative disorders
Current development stage
For Pharmaceutical development: TRL4 - POC & Safety of candidate drug formulation is ... More | Tsvelikhovsky Dmitry | |
New Ti(IV) metal complexes of Salan-ligands for Cancer treatment with reduce side effects (No. 2497)
Background
Metal based anti-tumor therapeutics Cisplatin and Carboplatin are two of the most widely prescribed anticancer agents.
However, not all tumors can be treated with Cisplatin. In addition, Cisplatin may cause an extremely toxic ... More | Tshuva Edit | |
Categories:
Life sciences and Biotechnology
Technology Keywords:
Drug Development, PPARD, Obesity, Glycogen Preserving, Lipid Metabolism, Wound Healing
Development Stage:
In silico, Identification of lead molecules, in vitro ... More | Goldblum Amiram | |
Category
LifeSciences and Biotechnology
Keywords
cancer, chemotherapy, prodrug
Current development stage
For Pharmaceutical development: TRL3 - hypothesis testing and intial POC demonstrated in limited # of in-vitro models
Choose ... More | Gibson Dan | |
Categories
Superactive High Afinity Leptin antagonist, mutein, multiple sclerosis, inflammatory bowel syndrome, rheumatoid arthritis, fibrosis, cardiovascular disease, CKD Cachexia, Osteoarthritis
Development Stage
(1) In vivo tests in ... More | Gertler Arieh | |
Our Innovation:
Drug-eluting stents (DES) are widely used in intravascular intervention.
The current technology is based on crystallization of drug onto stent surface (with no- polymer) Coating process is resulting in high yield coatings that ... More | Domb Abraham | |
Additional information will be provided upon request
More | Shoseyov Oded | |
Application
Congestive heart failure (CHF) is a chronic progressive disease that affects the pumping power of heart muscles. The disease is one of the leading causes of death and disability in the world. Almost 6 million Americans now suffer ... More | Lichtstein David |