Projects related to 46-2019-10785

Results Found (24)
Technology NameBriefcaseLead Researcher
Background Most cancers are unstable and highly susceptible to cell death; hence tumors represent a steady-state picture of unregulated proliferation as well as ongoing cell death. Therefore, substantial levels of tumor specific DNA may be ...
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Hellman Asaf
  Highly sensitive, self formed and simple to fabricate nano junction devices changing resistance in the presence of minute concentration of volatile gases:   Background Detectors of volatile gas, including combustible gases, are essential ...
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Yerushalmi Roie
Background   Current cancer diagnostic-methods rely on descriptive histopathological data. New technology measures patient genomic data against detailed classification of cancer types from databases of measured  tumor -genomic expression ...
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Smith Yoav
  Background Mutations in specific genes or proteins variability can dramatically enhance our probability to get cancer. Similarly, genetic variability could have the opposite effect and actually protect us from cancer, other diseases and even ...
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Tabach Yuval
Background To date, clinical tests that assess the level of malignancies from patient biopsies rely almost inclusively on histological analysis for specific markers and morphological cues as well as on genetic data i.e mutation analysis. In ...
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Benny Ofra
  Background Zinc and copper are essential metal-ions for numerous biological processes.  Their levels are tightly maintained in all body organs. Impairment of serum Zn2+ to Cu2+ ratio (ZCR) was found to correlate with many disease states, ...
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Yitzchaik Shlomo
  Background Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is characterized by chronic relapsing intestinal inflammation. To date several biomarkers are used for the diagnosis of IBD, such as CRP (blood) and ...
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Froy Oren
Background In the brain, α-Synuclein (α-Syn) protein is associated with the pathogenesis and progression of Parkinson’s disease and the related synucleinopathies, neurodegenerative diseases characterised by the abnormal accumulation of ...
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Sharon Ronit
  Background Recent reports claim that about 38% of human breast cancers may contain sequences related to MMTV. Antibodies generated against mouse lymphoma cells that harbor the virus MMTV (mouse mammary tumor virus) were used to recognize ...
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Hochman Jacob
Background Aphasia is an impairment of language, affecting speech and comprehension of speech and the ability to read and write and is the result of damage to the brain, most commonly from stroke (could also occur due to head trauma, brain ...
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Grodzinsky Yosef
  https://elsc.huji.ac.il/faculty-staff/yosef-grodzinsky   Background Language disorders affect up to 5% of all children and account for close to 20% of children with disabilities who receive special education. Language disorders make ...
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Grodzinsky Yosef
Category LifeSciences and BioTechnology    Keywords colorectal cancer, gut microbiota, personalized medicine Current development stage               For Pharmaceutical development: TRL4 - POC & Safety of candidate drug formulation is ...
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Ben-Neriah Yinon
The Citri Lab at the Hebrew University is developing a technology for quantitative psychiatry, relevant to the parsing of treatment modalities to patient populations. Diagnosing and treating psychiatric disorders is notoriously dependent on the ...
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Citri Ami
Background Valproic acid (VPA) is a first line antiepileptic and CNS drug (Epilepsy, neuropathic pain, bipolar disorders etc) Multivalent action of VPA is highly advantageous, promising improved efficacy with reduced side effects for ...
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Bialer Meir
Background Emulsification in aqueous media is not effective for the encapsulation of hydrophilic drugs. Peptides and proteins may deteriorate when exposed to aqueous-organic interfaces Neuropeptides are potent CNS neuromodulators and have many ...
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Domb Abraham
  Additional information will be provided upon request
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Domb Abraham
Category LifeSciences and BioTechnology    Keywords Natural compounds, Synthetic compounds, Neurodegenerative disorders Current development stage For Pharmaceutical development: TRL4 - POC & Safety of candidate drug formulation is ...
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Tsvelikhovsky Dmitry
Categories: Life Science & Biotechnology Technology Keywords: Nasal administration, CNS active oil,  neurodegenerative diseases, CNS Development Stage: Formulation and experiments in animals Patent Status: US  patent application ...
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Touitou Elka
Background Parkinson’s Disease (PD) is a progressive neurodegenerative disease caused by the loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). As the disease progresses the number of dopaminergic neurons decreases. ...
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Atlas Daphne
Background  Parkinson disease (PD) is a long-term, progressive neurodegenerative disorder of the central nervous system, which results in motor and non-motor dysfunction. The disease is primarily related to loss of dopaminergic ...
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Sharon Ronit
  Category LifeSciences and BioTechnology    Keywords Diagnosis, Alzheimer’s disease, cfDNA, Liquid biopsy, Current development stage General list: TRL3 Experimental proof of concept               Opportunity It is estimated that ...
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Dor Yuval
ApplicationValproic Acid (VPA) is used alone or with other medications to treat certain types of seizures such as epileptic seizures. It is also used to prevent migraine headaches and to treat mania (episodes of frenzied, abnormally excited ...
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Bialer Meir
  Category Food & Environment Keywords Molecular genetic chip, smuggling, wildlife, veterinary forensics Current development stage General list: TRL2  Technology Concept Formulated         Collaboration Opportunity Sponsored Research ...
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Kahila Bar-Gal Gila