| Technology Name | Briefcase | Lead Researcher |
|---|---|---|
Background:
Dental disorders occur when there are changes in oral hygiene, diet, medicaments or age.
Our Innovation
Novel dental coating that delivers therapeutics over time, as required, in response to sensed changes in acidic/basic conditions ... More | Friedman Michael | |
Background
With advances in biotechnology, nasal drug delivery is increasingly becoming a more viable alternative to oral and injectable routes of administration for an increasing number of drugs, including peptides.
Our Innovation
Platform ... More | Touitou Elka | |
Background
Most active pharmaceutical ingredients (APIs) are not suitable for “passive” loading into nano-liposomes. The desired concentration in the nano-liposomes is hard to achieve. Consequently, the therapeutic efficacy in humans is not ... More | Goldblum Amiram | |
Background
Emulsification in aqueous media is not effective for the encapsulation of hydrophilic drugs. Peptides and proteins may deteriorate when exposed to aqueous-organic interfaces
Neuropeptides are potent CNS neuromodulators and have many ... More | Domb Abraham | |
Background
Age-Related Macular Degeneration (AMD) and Diabetic Retinopathy (DR) are leading causes of blindness in the Western world. Both are characterized by pathological angiogenesis in the various eye structures.
With high prevalence in ... More | Willner Itamar | |
Additional information will be provided upon request
More | Domb Abraham | |
Background
Micro-emulsions are formed more or less spontaneously when their components are brought into contact. They have been the only successful delivery systems for certain types of pharmaceutical compounds, particularly compounds such as ... More | Domb Abraham | |
Background
Emulsification in aqueous media is not effective for the encapsulation of hydrophilic drugs. Peptides and proteins may deteriorate when exposed to aqueous-organic interfaces
Neuropeptides are potent CNS neuromodulators and have many ... More | Domb Abraham | |
Background
Many of today’s leading compounds and drugs in pipeline fail to reach clinical stages due to poor oral bioavailability. In addition, Increase in oral bioavailability leads a lower inter and intra subject variability.
Our ... More | Domb Abraham | |
Background
The release of targeted drugs is often achieved by attaching the drug load to a carrier through specific peptide sequences which are cleaved by proteases that are highly expressed at the desired location.
Cathepsins proteases, ... More | Blum Galia | |
Background
Peptides are key players in a variety of physiological and pathological processes and play very important roles in modulating various cell functions.
One of the most important challenges developing peptide drugs is the lack of ... More | Gilon Chaim | |
Background
Multiple strategies exist for the targeted treatment of different cell pathologies. One ongoing challenge is the introduction of therapeutic molecules into cells. Current approaches rely on viral vectors, electroporation, or carriers. ... More | Shenhar Roy | |
Categories:
Life Science & Biotechnology
Technology Keywords:
Nasal administration, CNS active oil, neurodegenerative diseases, CNS
Development Stage:
Formulation and experiments in animals
Patent Status:
US patent application ... More | Touitou Elka | |
Once-daily, sustained-release Sirolimus delivery system
Categories
Oral Cavity, Oncology/Cancer, Sustained Release, Drug Delivery
Development Stage
Prototypes tested in vitro; pharmokinetic and pharmacodynamic testing in human volunteers ... More | Friedman Michael | |
Background
The physical size of protein drugs and their susceptibility to degradation are key determinates that make them more dependent on drug delivery technologies. However formulating protein delivery systems so that they maintain their ... More | Barenholz Yechezkel | |
Oral Dosage Form for Immediate and Prolonged Action of Cannabinoids
Categories
Cannabinoids, Drug Delivery, Novel Carrier, Oral Formulation
Development Stage
In-vivo proof of concept
Patent Status
PCT patent application filed
Market ... More | Touitou Elka | |
Current Development Stage
TRL 9 Ready for mass production
Our Innovation
Pouch drug delivery system (web- like films) for dermal, transdermal and nail administration of drugs and actives for various treatments
Applied to the nail or ... More | Touitou Elka | |
Categories
Cannabinoids, Drug Delivery, Novel Carrier, Oral Formulation
Development Stage
In-vivo proof of concept
Patent Status
PCT patent application filed
Market
Improved delivery of cannabinoids is a real need and has an increasing ... More | Touitou Elka | |
Keywords
Innovative carrier, Nasal administration, Delivery to brain, Treatment of pain, disorders in Parkinson's disease, Multiple Sclerosis, Alzheimer, Epilepsy and brain trauma
Current development stage
Tested in animal model for ... More | Touitou Elka | |
Category
Prolonged release oral tablets
Keywords
Cannabinoids, Cannabis, tablets, oral administration
Application
In recent years, the medical use of cannabis and its derivatives has become widely accepted in the medical profession. IN ... More | Friedman Michael | |
BackgroundAccording to the World Health Organization approximately 422 million people currently suffer from diabetes. Type-I diabetes patients are characterized by their pancreas β-cells dysfunction and thereby absence of insulin secretion. ... More | Willner Itamar |