Projects related to 6-2018-5675

Results Found (26)
Technology NameBriefcaseLead Researcher
  Category LifeSciences and BioTechnology    Keywords Diabetes, FE-S Proteins, Metabolic   Current development stage TRL2 – Research ideas and protocols developed Our Innovation The finding by HUJI researchers uncovers a novel structure ...
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Nechushtai Rachel
  Categories Fatty liver, metabolic syndrome, obesity    Development Stage Drug at preclinical stage  Background Fatty liver disease - Non alcoholic fatty liver disease (NAFLD) is  a continuum of diseases that include simple steatosis and ...
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Tirosh Oren
  Categories Superactive High Afinity Leptin antagonist, mutein, multiple sclerosis, inflammatory bowel syndrome, rheumatoid arthritis, fibrosis, cardiovascular disease, CKD Cachexia, Osteoarthritis Development Stage (1) In vivo tests in ...
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Gertler Arieh
Yousef Najajreh, Al Quds University   Reducing Body Weight and Glucose Levels  & Improving Cognitive Function Categories Small molecule, obesity Development Stage Successful demonstration of efficacy in mice Patent Status  US  Granted ...
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Avraham Yosefa
Prof. Yaron Ilan, Department of Human Nutrition and Metabolism and Liver Unit Hadassah Hospital Cannabinoids/endocannabinoids and/or capsaicin or cannabidiol, improve both liver and brain functions   Categories Nutrition and Metabolism, ...
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Avraham Yosefa
  Category Life Sciences and Biotechnology    Keywords Type 2 Diabetes, Peptide, Insulin, Fatty liver, Glucose. Current development stage TRL3 Experimental proof of concept       Our Innovation Based on a provocative working hypothesis, ...
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Ben-Sasson Shmuel
  Categories Small molecules, anti-inflammatory treatment Development Stage In-vivo proof of concept Patent Status Patent application filed Market Inflammation indications: acute pancreatitis, acute live damage, fatty liver damage, ...
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Weinstock-Rosin Marta
Category LifeSciences and BioTechnology      Application Primary human hepatocytes are isolated from organs rejected from transplantation. Cells are expensive, show massive batch-to-batch variability and fail to proliferate in culture. ...
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Nahmias Yaakov
  Category Life Sciences and Biotechnology    Keywords Liver, RNA, miRNA Current development stage TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal modelvvvid demonstrated in  defined animal ...
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Soreq Hermona
Category Chemistry & Materials    Keywords Synthetic, natural, cyclization Current development stage General list: TRL4 Technology validated in lab      Application Many important biochemical compounds and drugs of natural origin ...
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Tsvelikhovsky Dmitry
  Categories: Life science and biotechnology Technology Keywords: Oncology, cancer drug resistance , chemotherapy, prodrug Development Stage: Preliminary POC with supporting in-vivo data Application Although FDA approved Pt(II) drugs are ...
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Gibson Dan
Category Chemistry&Materials    Keywords α-enaminone, heterocycles, cyclization Current development stage General list: TRL2  Technology Concept Formulated        Application Oxazine, azaspirone, quinolines, quinolinone, and ...
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Tsvelikhovsky Dmitry
Category Chemistry & Materials    Keywords Synthesis cycles;  hydroxyalkenoic acids;  lactones;  palladium;  regioselectivity Current development stage TRL2 -Research ideas and protocols developed  Application Methylene lactone ...
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Tsvelikhovsky Dmitry
  Category Life Sciences and Biotechnology    Keywords Cancer, Asthma, Inhibitor, Autotaxin Current development stage  Verified in several preclinical models Our Innovation A new approach to treat metastatic disease has been developed and ...
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Reich Reuven
  Keywords Epigenetics, Dual-specificity, Enzymes, anti-cancer Current Development Stage TRL3 - Hypothesis testing and initial POC demonstrated Application Cancer cells lose their epigenetic checks and balances followed by unscheduled ...
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Ben-Sasson Shmuel
  Categories: Life sciences & Biotechnology Technology Keywords: Muscular dystrophy, nonsense mutation, Duchenne, Becker, cystic fibrosis, genetic diseases, dystrophin   Development Stage: Proof of concept  Our Innovation A nonsense ...
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Karni Rotem
  Additional information will be provided upon request
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Mechoulam Raphael
  Additional information will be provided upon request
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Domb Abraham
  Additional information will be provided upon request
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Domb Abraham
  Keywords Antiepileptic drugs, 4-Aminobenzensulfonamides. Teratogenicity. Carbonic Anhydrase Inhibition Current development stage TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal ...
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Bialer Meir
Category Life Sciences and Bio Technology    Keywords Iterative Stochastic Elimination (ISE), Ligands, TLRs Current development stage TRL3 - hypothesis testing and intial POC demonstrated in limited # of in-vitro ...
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Goldblum Amiram
Category Life Sciences and Biotechnology    Keywords AMD, Angiogenic, VEGF, METAP2 Current development stage TRL3 Experimental proof of concept         Application Age Related Macular Degeneration (AMD) is the leading cause of blindness ...
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Benny Ofra
  Categories: Life Science & Biotechnology Technology Keywords: Small molecules, medicinal chemistry, Neural Regenerative Medicine, Neurotropic drugs Development Stage: Preclinical, drug discovery Patent Status: US Provisional Patent ...
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Tsvelikhovsky Dmitry
  Category Metabolic diseases Keywords Abdominal obesity, obesity Current development stage Pharmaceutical development: TRL2  Hypothesis Formulated        Collaboration Opportunity Sponsored Research with an option to License Research ...
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Monsonego-Ornan Efrat