Projects related to 6-2018-5690

Results Found (22)
Technology NameBriefcaseLead Researcher
Categories Oncology, Cancer, Diagnostics Development Stage In vitro proof of concept and small animals Patent Status PCT application filed Market Cancer testing is currently one of the most important growth opportunities diagnostics ...
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Karni Rotem
Background Currently there are no molecules that can directly inhibit the activity of splicing factors. We created decoy oligonucleotides that directly bind and inhibit the splicing activity of splicing factors without affecting their ...
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Karni Rotem
Background Epigenome editing by DNA methylation or demethylation of regulatory sequences are widely required in medicine and in biomedical research, but current technologies are non-specific and provide unpredictable effects. This technology ...
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Hellman Asaf
  Background Mutations in specific genes or proteins variability can dramatically enhance our probability to get cancer. Similarly, genetic variability could have the opposite effect and actually protect us from cancer, other diseases and even ...
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Tabach Yuval
Keywords cell free DNA diagnosis, liquid biopsies, methylation patterns, histone modification Current development stage   TRL3 - hypothesis testing and intial POC demonstrated in limited # of in-vitro modelsApplication The existing sequence ...
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Friedman Nir
Background Hyperlipidemia is a widespread condition that affects as many as one-third of adults and an increasing number of children in developed countries. Its pathogenesis mechanisms are only partly understood. The small non-coding microRNAs ...
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Soreq Hermona
A novel and personalized method for identifying the optimal anti-cancer treatment, through simultaneous detection of unique tumor sensitivities to multiple drugs or drug combinations in a multiplex manner, (this can be done) in vitro on cancer ...
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Willner Itamar
Background The therapeutic activity of most anticancer drugs in clinical use is limited by their general toxicity to proliferating cells, including some normal cells. Although chemists continue to develop novel cytotoxic agents with unique ...
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Willner Itamar
  Category Life Sciences and Biotechnology    Keywords Metabolic Syndrome, Transfer RNA fragments, Fatty liver disease, Diagnostics, Antisense oligonucleotide therapeutics, Biomarkers, Hepatic hyperlipidemia Current development stage For ...
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Soreq Hermona
  Category LifeSciences and BioTechnology    Keywords epilepsy, rare disease, gene therapy Current development stage For pharmaceutical development: TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal ...
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Aqeilan Rami
  Application Improved electrical connections between neurons and electronic devices for human-device improved interface and for research Highlights The ring-like Stable Protein 1 (SP1) is a homo-dodecamer with an outer diameter of 11nm and ...
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Spira Micha E
Background Micro- and nano-electronics underpin a significant part of the global economy. The global turnover of the sector was $310 billion in 2012. The value of products comprising micro- and nanoelectronics components represents around $215 ...
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Porath Danny
  Highly sensitive, self formed and simple to fabricate nano junction devices changing resistance in the presence of minute concentration of volatile gases:   Background Detectors of volatile gas, including combustible gases, are essential ...
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Yerushalmi Roie
Background One of the main obstacles for successful cryopreservation of cells is the irreversible damage to cells organelles and membranes caused by uncontrolled growth of ice in super-cooled liquid. This has a crucial impact on organ, embryo, ...
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Braslavsky Ido
Background Our invention is a new method for the successful synthesis of Multi-phosphorylated peptides that applies different coupling protocols and paves the way for the efficient and routine synthesis of multi-phosphorylated peptides of ...
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FRIEDLER Assaf
Background There is a growing demand in the field of biological drugs for improved protein expression platforms. Consequently there is a need for affordable manufacturing methods. Our Innovation A new concept of vector design that incorporates ...
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Tirosh Boaz
Background TD-test kit is a simple modification of the standard disk-diffusion assay that allows the semi-quantitative evaluation of survival rate and killing dynamics of Bacteria. The TDTest enables the detection of tolerant and persistent ...
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Balaban Natalie
Fills the gap between crystallography and optical imaging    Background Information about macromolecules is encoded in their shape and the way they are assembled. X-ray scattering methods are important tools for investigating the structure and ...
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Raviv Uri
Background        Chicken embryonic fibroblasts (CEFs) are commonly used for the production of vaccines and are a source material for cultured meat. Fibroblasts are contact-dependent limiting their large-scale production to carrier beads capable ...
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Nahmias Yaakov
Background The human brain is comprised of water, proteins and lipids,  which are distributed in different regions of the brain and in various pathological states. As yet, it remains a major challenge to localize and quantify these molecules ...
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Mezer Aviv