Projects related to 12-2018-5686

Results Found (24)
Technology NameBriefcaseLead Researcher
Background Basic taste qualities like sweet, bitter, sour, salty and umami serve specific functions in identifying food components found in the diet of humans and animals, and are recognized by bitter taste receptors in the oral cavity. It is ...
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Niv Masha
  Our Innovation Our state-of-the-art  liquid nanotechnology is set to revolutionize the NMR spectroscopy of mixtures. Uses easily available materials as well as novel formulations of specifically tailored solvent mixtures and/or novel ...
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Hoffman Roy
Background We have developed a new type of a compact scanning Micro-ellipsometer that operates with a spatial resolution on the sub 10-micron and over a broad spectral range. See Figure (next page). The Micro-ellipsometer can accurately ...
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Rapaport Ronen
Background: Dental disorders occur when there are changes in oral hygiene, diet, medicaments or age. Our Innovation Novel dental coating that delivers therapeutics over time, as required, in response to sensed changes in acidic/basic conditions ...
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Friedman Michael
  Background With advances in biotechnology, nasal drug delivery is increasingly becoming a more viable alternative to oral and injectable routes of administration for an increasing number of drugs, including peptides. Our Innovation Platform ...
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Touitou Elka
Background Most active pharmaceutical ingredients (APIs) are not suitable for “passive” loading into nano-liposomes. The desired concentration in the nano-liposomes is hard to achieve. Consequently, the therapeutic efficacy in humans is not ...
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Goldblum Amiram
Background Emulsification in aqueous media is not effective for the encapsulation of hydrophilic drugs. Peptides and proteins may deteriorate when exposed to aqueous-organic interfaces Neuropeptides are potent CNS neuromodulators and have many ...
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Domb Abraham
Background Age-Related Macular Degeneration (AMD) and Diabetic Retinopathy (DR) are leading causes of blindness in the Western world. Both are characterized by pathological angiogenesis in the various eye structures. With high prevalence  in  ...
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Willner Itamar
  Additional information will be provided upon request
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Domb Abraham
Background  Micro-emulsions are formed more or less spontaneously when their components are brought into contact.  They have been the only successful delivery systems for certain types of pharmaceutical compounds, particularly compounds such as ...
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Domb Abraham
Background Emulsification in aqueous media is not effective for the encapsulation of hydrophilic drugs. Peptides and proteins may deteriorate when exposed to aqueous-organic interfaces Neuropeptides are potent CNS neuromodulators and have many ...
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Domb Abraham
Background        Many of today’s leading compounds and drugs in pipeline fail to reach clinical stages due to poor oral bioavailability. In addition, Increase in oral bioavailability leads a lower inter and intra subject variability. Our ...
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Domb Abraham
Background The release of targeted drugs is often achieved by attaching the drug load to a carrier through specific peptide sequences which are cleaved by proteases that are highly expressed at the desired location. Cathepsins proteases, ...
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Blum Galia
Background Peptides are key players in a variety of physiological and pathological processes and play very important roles in modulating various cell functions. One of the most important challenges developing peptide drugs is the lack of ...
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Gilon Chaim
Categories: Life Science & Biotechnology Technology Keywords: Nasal administration, CNS active oil,  neurodegenerative diseases, CNS Development Stage: Formulation and experiments in animals Patent Status: US  patent application ...
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Touitou Elka
Once-daily, sustained-release Sirolimus delivery system Categories Oral Cavity, Oncology/Cancer, Sustained Release, Drug Delivery Development Stage Prototypes tested in vitro; pharmokinetic and pharmacodynamic testing in human volunteers ...
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Friedman Michael
Background The physical size of protein drugs and their susceptibility to degradation are key determinates that make them more dependent on drug delivery technologies. However formulating protein delivery systems so that they maintain their ...
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Barenholz Yechezkel
Oral Dosage Form for Immediate and Prolonged Action of Cannabinoids     Categories  Cannabinoids, Drug Delivery, Novel Carrier, Oral Formulation Development Stage In-vivo proof of concept Patent Status PCT patent application filed Market ...
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Touitou Elka
  Current Development Stage TRL 9 Ready for mass production   Our Innovation Pouch drug delivery system (web- like films) for dermal, transdermal and nail  administration of drugs and actives for various treatments Applied to the nail or ...
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Touitou Elka
  Categories Cannabinoid Administration, Formulation, Drug Delivery, Novel Carriers, Transdermal Formulation, Nasal Formulation, Oral formulation Development Stage In-vivo proof of concept Patent Status Several patent applications – new ...
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Touitou Elka
  Categories Cannabinoids, Drug Delivery, Novel Carrier, Oral Formulation Development Stage In-vivo proof of concept Patent Status PCT patent application filed Market Improved delivery of cannabinoids is a real need and has an increasing ...
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Touitou Elka
Keywords Innovative carrier, Nasal administration, Delivery to brain, Treatment of pain, disorders in Parkinson's disease, Multiple Sclerosis, Alzheimer, Epilepsy and brain trauma Current development stage Tested in animal model for ...
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Touitou Elka
Category Prolonged release oral tablets    Keywords Cannabinoids, Cannabis, tablets, oral administration  Application In recent years, the medical use of cannabis and its derivatives has become widely accepted in the medical profession.  IN ...
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Friedman Michael
BackgroundAccording to the World Health Organization approximately 422 million people currently suffer from diabetes. Type-I diabetes patients are characterized by their pancreas β-cells dysfunction and thereby absence of insulin secretion. ...
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Willner Itamar