Projects related to 6-2018-4548

Results Found (12)
Technology NameBriefcaseLead Researcher
  Categories Superactive High Afinity Leptin antagonist, mutein, multiple sclerosis, inflammatory bowel syndrome, rheumatoid arthritis, fibrosis, cardiovascular disease, CKD Cachexia, Osteoarthritis Development Stage (1) In vivo tests in ...
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Gertler Arieh
  Background Mast cells (MCs) are a type of white blood cell active in the immune system. They are produced in the bone marrow and play a key role in the inflammatory process.  Additionally, they are the primary driver of allergic reactions, ...
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Levi-Schaffer Francesca
  Background DNA mutations in mitochondrial proteins/enzymes (nuclear encoded) that may lead to disease are present in approximately 1 in 8,000 individuals. Any treatment for mitochondrial diseases must be capable of targeting and crossing the ...
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Galski- Lorberboum Haya
  Background It was recently shown that enhanced expression of NAF-1, is associated with different cancers, including breast, prostate, gastric, cervical, liver, and laryngeal. Silencing of NAF-1 expression in breast, or gastric, cancer cells ...
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Nechushtai Rachel
  Our Innovation   Based on a provocative working hypothesis, DiBait (DB) has identified the molecular origin of insulin resistance (IR): IR may induced via post-translational modification (PTM) of these proteins upon starvation and in fatty ...
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Ben-Sasson Shmuel
  Category Life Sciences and Bio Technology    Keywords Nanoparticles, Neuropeptides, Intranasal delivery Current development stage TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal modelHighlights ...
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Domb Abraham
Fills the gap between crystallography and optical imaging  Category Chemistry & Materials    Keywords X-ray scattering, Supramolecular, Self-Assembled Current development stage Functioning software programApplication Information ...
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Raviv Uri
Keywords Platform technology, Intestinal permeability, Lipophilic Prodrug Charge Masking, peptides, oral bioavailability Current development stage TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal ...
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Gilon Chaim
Keywords Cell death, dopaminergic (DA) neurons, L-Dopa-induced dyskinesia (LID) Current development stage TRL3 - hypothesis testing and initial POC demonstrated in limited number of in-vitro models Application Parkinson’s Disease (PD) is a ...
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Atlas Daphne
  Category Life Sciences and Biotechnology    Keywords Liver, RNA, miRNA Current development stage TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal modelvvvid demonstrated in  defined animal ...
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Soreq Hermona
Once-daily, sustained-release Sirolimus delivery system Categories Oral Cavity, Oncology/Cancer, Sustained Release, Drug Delivery Development Stage Prototypes tested in vitro; pharmokinetic and pharmacodynamic testing in human volunteers ...
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Friedman Michael