Projects related to 6-2014-3018

Results Found (20)
Technology NameBriefcaseLead Researcher
Categories Oncology, Cancer, Diagnostics Development Stage In vitro proof of concept and small animals Patent Status PCT application filed Market Cancer testing is currently one of the most important growth opportunities diagnostics ...
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Karni Rotem
  Categories Treatment of cancer, neurodegeneration and infectious diseases. Development Stage In vitro proof of concept; in vivo POC Patent Status PCT publication number : WO2016/142948Highlights A new technology to inhibit the activity ...
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Karni Rotem
Background Epigenome editing by DNA methylation or demethylation of regulatory sequences are widely required in medicine and in biomedical research, but current technologies are non-specific and provide unpredictable effects. This technology ...
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Hellman Asaf
  Category LifeSciences and BioTechnology Keywords Genomics, Cancer Resistance, Species Current development stage General list: TRL3 Experimental proof of concept             Application Mutation in specific genes or variability in ...
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Tabach Yuval
Keywords cell free DNA diagnosis, liquid biopsies, methylation patterns, histone modification Current development stage   TRL3 - hypothesis testing and intial POC demonstrated in limited # of in-vitro modelsApplication The existing sequence ...
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Friedman Nir
Keywords Multiplex PCR, PCR, cfDNA, Research tool, Liquid Biopsy, DNA methylation, cell-free DNA Current development stage TRL5 Technology validated in relevant environementApplication PCR on bisulfite-treated DNA, followed by next ...
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Dor Yuval
A novel and personalized method for identifying the optimal anti-cancer treatment, through simultaneous detection of unique tumor sensitivities to multiple drugs or drug combinations in a multiplex manner, (this can be done) in vitro on cancer ...
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Willner Itamar
  Category LifeSciences and BioTechnology    Keywords Cancer, Oncology, Nanoparticles, Metal-Organic Framework Nanoparticles, NMOF,  miRNA, targeted therapy, nanotechnology, Biomarker Current development stage General list: TRL3 ...
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Willner Itamar
  Background DNA mutations in mitochondrial proteins/enzymes (nuclear encoded) that may lead to disease are present in approximately 1 in 8,000 individuals. Any treatment for mitochondrial diseases must be capable of targeting and crossing the ...
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Galski- Lorberboum Haya
Keywords Anti-Aging, Vascular Endothelial Growth Factor Current development stage TRL3 - hypothesis testing and intial POC demonstrated in limited number of in-vitro modelsApplication With continuous increase in the elderly population, many ...
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Keshet Eli
Once-daily, sustained-release Sirolimus delivery system Categories Oral Cavity, Oncology/Cancer, Sustained Release, Drug Delivery Development Stage Prototypes tested in vitro; pharmokinetic and pharmacodynamic testing in human volunteers ...
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Friedman Michael
Our Innovation   The finding by HUJI researchers uncovers a novel structure of an outer mitochondrial membrane [Fe-S] protein (mitoNEET) determined by X-ray crystallography (Fig 1)  MitoNEET is an outer mitochondrial membrane protein that ...
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Nechushtai Rachel
Background Fatty liver disease - Non alcoholic fatty liver disease (NAFLD) is  a continuum of diseases that include simple steatosis and non-alcoholic steatohepatitis (NASH) ultimately leading to cirrhosis, hepatocellular carcinoma (HCC) and/or ...
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Tirosh Oren
  Categories Superactive High Afinity Leptin antagonist, mutein, multiple sclerosis, inflammatory bowel syndrome, rheumatoid arthritis, fibrosis, cardiovascular disease, CKD Cachexia, Osteoarthritis Development Stage (1) In vivo tests in ...
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Gertler Arieh
Yousef Najajreh, Al Quds University   Reducing Body Weight and Glucose Levels  & Improving Cognitive Function Categories Small molecule, obesity Development Stage Successful demonstration of efficacy in mice Patent Status  US  Granted ...
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Avraham Yosefa
Prof. Yaron Ilan, Department of Human Nutrition and Metabolism and Liver Unit Hadassah Hospital Cannabinoids/endocannabinoids and/or capsaicin or cannabidiol, improve both liver and brain functions   Categories Nutrition and Metabolism, ...
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Avraham Yosefa
  Our Innovation   Based on a provocative working hypothesis, we most probably identified the molecular origin of insulin resistance (IR). Systemic IR is induced via post-translational modification (PTM) of liver key regulatory proteins. We ...
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Ben-Sasson Shmuel
  Categories Small molecules, anti-inflammatory treatment Development Stage In-vivo proof of concept Patent Status Patent application filed Market Inflammation indications: acute pancreatitis, acute live damage, fatty liver damage, ...
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Weinstock-Rosin Marta
Category LifeSciences and BioTechnology      Application Primary human hepatocytes are isolated from organs rejected from transplantation. Cells are expensive, show massive batch-to-batch variability and fail to proliferate in culture. ...
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Nahmias Yaakov
  Category Life Sciences ,pharma Keywords Non-alcoholic fatty liver disease, NAFLD, Liver Toxicity, metabolic diseases, Current development stage General list: TRL3 Experimental proof of concept              Partnership ...
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Tirosh Oren