| Technology Name | Briefcase | Lead Researcher |
|---|---|---|
Categories
Oncology, Cancer, Diagnostics
Development Stage
In vitro proof of concept and small animals
Patent Status
PCT application filed
Market
Cancer testing is currently one of the most important growth opportunities diagnostics ... More | Karni Rotem | |
Categories
Treatment of cancer, neurodegeneration and infectious diseases.
Development Stage
In vitro proof of concept; in vivo POC
Patent Status
PCT publication number : WO2016/142948Highlights
A new technology to inhibit the activity ... More | Karni Rotem | |
Background
Epigenome editing by DNA methylation or demethylation of regulatory sequences are widely required in medicine and in biomedical research, but current technologies are non-specific and provide unpredictable effects. This technology ... More | Hellman Asaf | |
Category
LifeSciences and BioTechnology
Keywords
Genomics, Cancer Resistance, Species
Current development stage
General list: TRL3 Experimental proof of concept Application
Mutation in specific genes or variability in ... More | Tabach Yuval | |
Keywords
cell free DNA diagnosis, liquid biopsies, methylation patterns, histone modification
Current development stage
TRL3 - hypothesis testing and intial POC demonstrated in limited # of in-vitro modelsApplication
The existing sequence ... More | Friedman Nir | |
Keywords
Multiplex PCR, PCR, cfDNA, Research tool, Liquid Biopsy, DNA methylation, cell-free DNA
Current development stage
TRL5 Technology validated in relevant environementApplication
PCR on bisulfite-treated DNA, followed by next ... More | Dor Yuval | |
A novel and personalized method for identifying the optimal anti-cancer treatment, through simultaneous detection of unique tumor sensitivities to multiple drugs or drug combinations in a multiplex manner, (this can be done) in vitro on cancer ... More | Willner Itamar | |
Category
LifeSciences and BioTechnology
Keywords
Cancer, Oncology, Nanoparticles, Metal-Organic Framework Nanoparticles, NMOF, miRNA, targeted therapy, nanotechnology, Biomarker
Current development stage
General list: TRL3 ... More | Willner Itamar | |
Background
DNA mutations in mitochondrial proteins/enzymes (nuclear encoded) that may lead to disease are present in approximately 1 in 8,000 individuals.
Any treatment for mitochondrial diseases must be capable of targeting and crossing the ... More | Galski- Lorberboum Haya | |
Keywords
Anti-Aging, Vascular Endothelial Growth Factor
Current development stage
TRL3 - hypothesis testing and intial POC demonstrated in limited number of in-vitro modelsApplication
With continuous increase in the elderly population, many ... More | Keshet Eli | |
Once-daily, sustained-release Sirolimus delivery system
Categories
Oral Cavity, Oncology/Cancer, Sustained Release, Drug Delivery
Development Stage
Prototypes tested in vitro; pharmokinetic and pharmacodynamic testing in human volunteers ... More | Friedman Michael | |
Our Innovation
The finding by HUJI researchers uncovers a novel structure of an outer mitochondrial membrane [Fe-S] protein (mitoNEET) determined by X-ray crystallography (Fig 1)
MitoNEET is an outer mitochondrial membrane protein that ... More | Nechushtai Rachel | |
Background
Fatty liver disease - Non alcoholic fatty liver disease (NAFLD) is a continuum of diseases that include simple steatosis and non-alcoholic steatohepatitis (NASH) ultimately leading to cirrhosis, hepatocellular carcinoma (HCC) and/or ... More | Tirosh Oren | |
Categories
Superactive High Afinity Leptin antagonist, mutein, multiple sclerosis, inflammatory bowel syndrome, rheumatoid arthritis, fibrosis, cardiovascular disease, CKD Cachexia, Osteoarthritis
Development Stage
(1) In vivo tests in ... More | Gertler Arieh | |
Yousef Najajreh, Al Quds University
Reducing Body Weight and Glucose Levels & Improving Cognitive Function
Categories
Small molecule, obesity
Development Stage
Successful demonstration of efficacy in mice
Patent Status
US Granted ... More | Avraham Yosefa | |
Prof. Yaron Ilan, Department of Human Nutrition and Metabolism and Liver Unit Hadassah Hospital
Cannabinoids/endocannabinoids and/or capsaicin or cannabidiol, improve both liver and brain functions
Categories
Nutrition and Metabolism, ... More | Avraham Yosefa | |
Our Innovation
Based on a provocative working hypothesis, we most probably identified the molecular origin of insulin resistance (IR). Systemic IR is induced via post-translational modification (PTM) of liver key regulatory proteins. We ... More | Ben-Sasson Shmuel | |
Categories
Small molecules, anti-inflammatory treatment
Development Stage
In-vivo proof of concept
Patent Status
Patent application filed
Market
Inflammation indications: acute pancreatitis, acute live damage, fatty liver damage, ... More | Weinstock-Rosin Marta | |
Category
LifeSciences and BioTechnology
Application
Primary human hepatocytes are isolated from organs rejected from transplantation. Cells are expensive, show massive batch-to-batch variability and fail to proliferate in culture. ... More | Nahmias Yaakov | |
Category
Life Sciences ,pharma
Keywords
Non-alcoholic fatty liver disease, NAFLD, Liver Toxicity, metabolic diseases,
Current development stage
General list: TRL3 Experimental proof of concept
Partnership ... More | Tirosh Oren |