| Technology Name | Briefcase | Lead Researcher |
|---|---|---|
Our Innovation
The finding by HUJI researchers uncovers a novel structure of an outer mitochondrial membrane [Fe-S] protein (mitoNEET) determined by X-ray crystallography (Fig 1)
MitoNEET is an outer mitochondrial membrane protein that ... More | Nechushtai Rachel | |
Background
Fatty liver disease - Non alcoholic fatty liver disease (NAFLD) is a continuum of diseases that include simple steatosis and non-alcoholic steatohepatitis (NASH) ultimately leading to cirrhosis, hepatocellular carcinoma (HCC) and/or ... More | Tirosh Oren | |
Categories
Superactive High Afinity Leptin antagonist, mutein, multiple sclerosis, inflammatory bowel syndrome, rheumatoid arthritis, fibrosis, cardiovascular disease, CKD Cachexia, Osteoarthritis
Development Stage
(1) In vivo tests in ... More | Gertler Arieh | |
Prof. Yaron Ilan, Department of Human Nutrition and Metabolism and Liver Unit Hadassah Hospital
Background
To date, there is no effective treatment of liver diseases with the related Hepatic-Encephalopathy symptoms. It is established that ... More | Avraham Yosefa | |
Our Innovation
Based on a provocative working hypothesis, we most probably identified the molecular origin of insulin resistance (IR). Systemic IR is induced via post-translational modification (PTM) of liver key regulatory proteins. We ... More | Ben-Sasson Shmuel | |
Categories
Small molecules, anti-inflammatory treatment
Development Stage
In-vivo proof of concept
Patent Status
Patent application filed
Market
Inflammation indications: acute pancreatitis, acute live damage, fatty liver damage, ... More | Weinstock-Rosin Marta | |
Category
LifeSciences and BioTechnology
Application
Primary human hepatocytes are isolated from organs rejected from transplantation. Cells are expensive, show massive batch-to-batch variability and fail to proliferate in culture. ... More | Nahmias Yaakov | |
Category
Life Sciences and Biotechnology
Keywords
Liver, RNA, miRNA
Current development stage
TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal modelvvvid demonstrated in defined animal ... More | Soreq Hermona | |
Category
Life Sciences ,pharma
Keywords
Non-alcoholic fatty liver disease, NAFLD, Liver Toxicity, metabolic diseases,
Current development stage
General list: TRL3 Experimental proof of concept
Partnership ... More | Tirosh Oren |