Projects related to 6-2008-1996

Results Found (9)
Technology NameBriefcaseLead Researcher
Our Innovation   The finding by HUJI researchers uncovers a novel structure of an outer mitochondrial membrane [Fe-S] protein (mitoNEET) determined by X-ray crystallography (Fig 1)  MitoNEET is an outer mitochondrial membrane protein that ...
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Nechushtai Rachel
Background Fatty liver disease - Non alcoholic fatty liver disease (NAFLD) is  a continuum of diseases that include simple steatosis and non-alcoholic steatohepatitis (NASH) ultimately leading to cirrhosis, hepatocellular carcinoma (HCC) and/or ...
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Tirosh Oren
  Categories Superactive High Afinity Leptin antagonist, mutein, multiple sclerosis, inflammatory bowel syndrome, rheumatoid arthritis, fibrosis, cardiovascular disease, CKD Cachexia, Osteoarthritis Development Stage (1) In vivo tests in ...
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Gertler Arieh
Prof. Yaron Ilan, Department of Human Nutrition and Metabolism and Liver Unit Hadassah Hospital Background To date, there is no effective treatment of liver diseases with the related Hepatic-Encephalopathy symptoms. It is established that ...
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Avraham Yosefa
  Our Innovation   Based on a provocative working hypothesis, we most probably identified the molecular origin of insulin resistance (IR). Systemic IR is induced via post-translational modification (PTM) of liver key regulatory proteins. We ...
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Ben-Sasson Shmuel
  Categories Small molecules, anti-inflammatory treatment Development Stage In-vivo proof of concept Patent Status Patent application filed Market Inflammation indications: acute pancreatitis, acute live damage, fatty liver damage, ...
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Weinstock-Rosin Marta
  Background Primary human hepatocytes are isolated from organs rejected from transplantation. Cells are expensive, show massive batch-to-batch variability and fail to proliferate in culture. Hepatocytes are routinely used by the pharmaceutical ...
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Nahmias Yaakov
Background Hyperlipidemia is a widespread condition that affects as many as one-third of adults and an increasing number of children in developed countries. Its pathogenesis mechanisms are only partly understood. The small non-coding microRNAs ...
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Soreq Hermona
  Background Non-alcoholic fatty liver disease (NAFLD) and associated diseases Non-alcoholic steatohepatitis (NASH), Cirrhosis, and Hepatocellular carcinoma (HCC) cost the US economy an estimated at $103 billion per year. Lipotoxicity is a major ...
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Tirosh Oren