Projects related to 7-2012-2783

Results Found (44)
Technology NameBriefcaseLead Researcher
  Categories Treatment of cancer, neurodegeneration and infectious diseases. Development Stage In vitro proof of concept; in vivo POC Patent Status PCT publication number : WO2016/142948Highlights A new technology to inhibit the activity ...
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Karni Rotem
  Category Medical SciencesHighlights Epigenome editing by DNA methylation or demethylation of regulatory sequences are widely required in medicine and in biomedical research, but current technologies are non-specific and provide ...
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Hellman Asaf
  Category LifeSciences and BioTechnology Keywords Genomics, Cancer Resistance, Species Current development stage General list: TRL3 Experimental proof of concept             Application Mutation in specific genes or variability in ...
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Tabach Yuval
Keywords cell free DNA diagnosis, liquid biopsies, methylation patterns, histone modification Current development stage   TRL3 - hypothesis testing and intial POC demonstrated in limited # of in-vitro modelsApplication The existing sequence ...
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Friedman Nir
  Category Life Sciences and Biotechnology    Keywords Liver, RNA, miRNA Current development stage TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal modelvvvid demonstrated in  defined animal ...
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Soreq Hermona
Keywords Multiplex PCR, PCR, cfDNA, Research tool, Liquid Biopsy, DNA methylation, cell-free DNA Current development stage TRL5 Technology validated in relevant environementApplication PCR on bisulfite-treated DNA, followed by next ...
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Dor Yuval
A novel and personalized method for identifying the optimal anti-cancer treatment, through simultaneous detection of unique tumor sensitivities to multiple drugs or drug combinations in a multiplex manner, (this can be done) in vitro on cancer ...
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Willner Itamar
  Category LifeSciences and BioTechnology    Keywords Cancer, Oncology, Nanoparticles, Metal-Organic Framework Nanoparticles, NMOF,  miRNA, targeted therapy, nanotechnology, Biomarker Current development stage General list: TRL3 ...
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Willner Itamar
  Categories Superactive High Afinity Leptin antagonist, mutein, multiple sclerosis, inflammatory bowel syndrome, rheumatoid arthritis, fibrosis, cardiovascular disease, CKD Cachexia, Osteoarthritis Development Stage (1) In vivo tests in ...
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Gertler Arieh
A specific therapy for treating this serious disease   Categories Mastocytosis, Cancer Development Stage Proof-of-concept, preclinical Patent Status Patent Pending Market Mastocytosis, Mast Cell Leukemia, AllergiesBackground Mast cells ...
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Levi-Schaffer Francesca
  Categories: Life science and biotechnology Technology Keywords: Oncology, cancer drug resistance , chemotherapy, prodrug Development Stage: Preliminary POC with supporting in-vivo data Application Although FDA approved Pt(II) drugs are ...
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Gibson Dan
The Application Most cancers are unstable and highly susceptible to cell death; hence tumors represent a steady-state picture of unregulated proliferation as well as ongoing cell death. Therefore, substantial levels of tumor specific DNA may be ...
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Hellman Asaf
  Categories Diagnostics,  Research Development Stage In vitro and in-vivo proof of concept; ongoing research Patent Status US, Europe and China applications filed based on WO 2017/025968  Background Fluorescence guided surgery is currently ...
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Yavin Eylon
Category Life Sciences and Biotechnology    Keywords Tumor, Digestive System, Microwave, Ablation, Cancer, Radiation Current development stage TRL2 - Hypothesis testing and initial POC;  ex-vivo    Application        Very small tumors ...
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Feldman Yuri
  Category Life Sciences and Biotechnology    Keywords Cathespin, Molecular Imaging, Cancer, CT, Computed Tomography, Current development stage TRL3 - Hypothesis testing and initial POC demonstrated in-vivo Application X-ray computed ...
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Blum Galia
  Categories Cancer, metastasis, drug, zinc enzyme inhibitor Development Stage Drug at preclinical stage  Background The process of cancer metastasis consists of a series of sequential events that requires deregulated proliferation and ...
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Breuer Eli
Keywords Cancer, Peptide, NAF-1 Current development stage Initial in-vivo studies completed Application It was recently shown that enhanced expression of NAF-1, is associated with different cancers, including breast, prostate, gastric, ...
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Nechushtai Rachel
  Category Medical Sciences, Stem cells, Small molecules Our Innovation Improved removal of PSCs may be obtained by identifying small molecules that selectively perturb crucial pathways in PSCs, and thus induce cell death in these cells ...
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Benvenisty Nissim
Dr. Sharon Merims, Hadassah Medical Center Category Life Sciences and Biotechnology    Keywords EGFR inhibitor, skin toxicity, topical Current development stage TRL3 - hypothesis testing and initial POC demonstrated in limited # of ...
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Benny Ofra
Keywords Glioblastoma multiforme, regulatory networks, target genes Current development stage TRL3 - hypothesis testing and initial POC demonstrated in-vitro Application Glioblastoma multiforme (GBM) is a common, very aggressive brain ...
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Hellman Asaf
  Category Life Sciences and Biotechnology    Keywords Cancer, Asthma, Inhibitor, Autotaxin Current development stage  Verified in several preclinical models Our Innovation A new approach to treat metastatic disease has been developed and ...
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Reich Reuven
  Keywords Epigenetics, Dual-specificity, Enzymes, anti-cancer Current Development Stage TRL3 - Hypothesis testing and initial POC demonstrated Application Cancer cells lose their epigenetic checks and balances followed by unscheduled ...
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Ben-Sasson Shmuel
  Additional information will be provided upon request
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Mechoulam Raphael
To date, clinical tests that assess the level of malignancies from patient biopsies rely almost inclusively on histological analysis for specific markers and morphological cues as well as on genetic data i.e mutation analysis. In spite of the ...
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Benny Ofra
Category LifeSciences and BioTechnology    Keywords Therapeutic Agents, Liposomes, Biochemistry, Doxorubicin, Sulfate, Alkyl Sulfonate, DoxilTM  Application Current preclinical and clinical data indicate that there is negligible release of ...
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Barenholz Yechezkel
  Additional information will be provided upon request
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Domb Abraham