Mycobacterium marinum bacteria-based vaccine for fish

Barkan Daniel, HUJI, Faculty of Agricultural, Food and Environmental Quality Sciences, The Koret School of Veterinary Medicine


  • M. marinum is a major causative agent of fish Mycobacteriosis, a common bacterial disease in many species of freshwater, brackish water and salt water fish - specifically harming food fish such as Sea Bass, H. S. Bass and Sea Bream, reared under intensive conditions.
  • M. marinum bacteria has several isolates, some are potentially zoonotic specifically harmful for marine and aquarium workers.
  • M. marinum bacteria harms zebrafish- a commonly used research model, and is considered a major problem in research facilities.
  • Today there is no effective vaccine against M. marinum bacteria. In addition, there are no prescribed medications against this bacteria.

Our Innovation

A new Mycobacterium marinum (M. marinum ) bacteria-based vaccine can be used as an  effective  vaccine against the Mycobacteriosis disease in fish.



  • Worldwide problem with a large market.
  • M. marinum bacteria harms zebrafish, and is considered a major problem in research facilities.
  • Sea Bass is one of the food fish harmed by M. marinum. In Israel for example, the high incidence of M. marinum, caused the fish growers to stop growing this species

Contact for more information:

Ilya Pittel
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