New Method to Culture Contact-Dependent Cells in Suspension

Nahmias Yaakov, HUJI, School of Computer Science and Engineering, Bio-Engineering


chicken embryonic fibroblasts, CEF, cell density, Human vaccines, veterinary vaccines, viral vaccines

Current development stage

  TRL4 Technology validated in lab             

Our Innovation

Methods and cell lines to improve density of Chicken Embryonic Fibroblasts (CEFs)

Chicken Embryonic Fibroblasts (CEFs) are commonly used in the industry, and as so, methods for improving large-scale industrial cell production are of need, specifically for vaccine production


CEF are routinely used to produce vaccines. The proposed technology can be used by pharmaceutical and biotechnology companies to develop human and veterinary viral and therapeutic vaccines. The expected increase in yield is up to 40-fold in comparison to current growing methods

The cell line is a continuous line of chicken embryo. The cells are free of endogenous sequences related to avian sarcoma and leukosis viruses and have normal fibroblastic morphology. The cells have higher proliferation rate and also can be subcultured infinite number of times

Contact for more information:

Mel Larrosa
VP Business Development Healthcare
Contact ME: