TEMPACE: A Temporary Pacemaker to Secure Transcatheter Aortic Valve Implantation (TAVI)

Nahmias Yaakov, HUJI, School of Computer Science and Engineering, Bio-Engineering


Pacemaker, Cardiology, Medical Device, Aortic stenosis

Current development stage

TRL3 - Hypothesis testing and initial POC is demonstrated


Transcatheter Aortic Valve Implantation (TAVI) is one of the fastest growing medical procedures worldwide for Aortis Stenosis Patients. However, abnormalities may cause Left Bundle Branch Block (LBBB) in approximately 25% of patients, requiring on average 3 days of Intensive care unit hospitalization while the patient is wired to an external temporary pacemaker. 

While LBBB may develop into a complete AV block requiring a permanent pacemaker, many patients stabilize without further procedures. Therefore, there is need for a safe and convenient way to protect a patient during the intermediate period, after which a decision whether to permanently implant a pacemaker can be taken.


Our Innovation

The researchers developed a device comprised of a small temporary pacemaker that fits on top a standard pacing lead during the TAVI procedure itself and used to rapidly pace the heart during the procedure to prevent movement.

Uniquely, if LBBB is diagnosed, the temporary pacemaker is threaded on top of the pacing lead into the right ventricle and actively fixed into the myocardial tissue.

  • TEMPACE device can be left in place over a required period.  
  • TEMPACE serves as a safety net to prevent LBBB evolvement into a complete AV block.


  • Aortic stenosis is a common heart problem caused by the narrowing of the aortic valve opening, thus restricting the blood flow from the left ventricle to the aorta. The aortic stenosis leads to chest pain, shortness of breath, swelling and ultimately heart failure.
  • Aortic stenosis is affecting around 2% of patients over 65 years old.


Contact for more information:

Mel Larrosa
VP Business Development Healthcare
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