A Method for Improvement of Protein Production in Mammalian Cells

Tirosh Boaz, HUJI, School of Medicine - IMRIC, School of Pharmacy- Institute for Drug Research


LifeSciences and BioTechnology   


Cell line productivity, Cell line engineering, Biosimilars

Current development stage

 TRL3 - hypothesis testing and intial POC demonstrated in limited # of in-vitro models



We suggest companies to engineer their cell line with a protein that endows cells with better growth and productivity.

Our Innovation

A new concept of vector design that incorporates a gene-specific enhanced translation elements and assess their performance in CHO cells

A single protein (oncoKIT) which improves growth and resilience to stress.


Generating stable expression of oncoKIT in production cell lines.


We offer companies that have their own propriety cells to use this for improvement. The proposed method to enhance protein expression has broad range of applications in R&D and biomanufacturing. The method helps to reduce the production costs and simplify the downstream processes of purification.

There is a growing demand in the field of biological drugs for improved protein expression platforms. Consequently there is a need for affordable manufacturing methods.

Contact for more information:

Shani Bullock
VP, Business Development, Healthcare
Contact ME: