Culturing Device for Evaluation of Oocytes and Embryos

Buxboim Amnon, HUJI, School of Computer Science and Engineering, Bio-Engineering
Wintner Oren, HUJI, School of Computer Science and Engineering


In-vitro fertilization (IVF) is becoming widespread worldwide, and in the developed world, up to 5% of children have been born following IVF procedures. Up to 17% of women have trouble conceiving; infertility rate increases to more than 35% for women ages over 35.   

A reliable method for early identifying of the oocytes and preimplantation embryos with the highest developmental competence is required to ensure healthy newborns

Our Innovation

MechanoPLate is a culturing device for oocytes / embryos that enables in situ continuous visualization and mechanical characterization during culture. The information acquired is used for evaluating the developmental quality of oocytes and embryos


  • Mechanoplate, compatible with time-lapse incubators. It is designed for culturing, imaging and mechanical profiling of a single oocyte or embryo, providing time-lapse imaging (TLI)  and mechanical profiling in one device
  • Relevant to both oocytes and embryo assessment


  • Undisturbed embryo culture
  • Continuous record of embryo development for quality control and standardization of morphologic assessment

The Opportunity

  • Cultivation of fertilized oocytes and the subsequent selection of embryos are central components in assisted reproductive market
  • Additional markets relevant for this technology are Animal Breeding Market. Developmental Biology Research  and Toxicity Testing Markets



Contact for more information:

Keren-Or Amar
VP, Business Development, Healthcare
Contact ME: