3058

Novel Compounds for Treatment and Prevention of Autism

Avraham Yosefa, HUJI, School of Medicine - IMRIC, School of Public Health
Berry Elliot, HUJI, School of Medicine - IMRIC, School of Public Health

Background:

Autism spectrum disorder (ASD) is one of the fastest growing developmental disability in the United States, represents a group of neurodevelopmental disorders characterized by impaired social interaction and communication as well as restricted and repetitive behavior. The underlying cause of autism is unknown and therapy is currently limited to targeting behavioral abnormalities. Currently, there are no medications that can cure Autism Spectrum Disorder (ASD) or treat the core symptoms

Highlights
  • Novel compound administered to the mother during pregnancy or to newborns (after birth) of families predisposed to "Autism" has the potential to prevent /ameliorate autistic symptoms.
  • No side effects in animal models. These results support further clinical studies.

Our Innovation

  • A novel compound that can be administered to mothers during pregnancy or newborns (after birth) in families predisposed to "autism"– it has the potential to prevent /ameliorate autistic symptoms.
  • A safe, non-teratogenic, natural occurring compound that can be consumed safely by human. Tested by in-vitro and in-vivo animal models of autism , both as a preventive and therapeutic drug.
  • When administered to mice, this compound reduced significantly restricted and stereotyped behaviors and interests. Moreover, it significantly increased the social interactions and communication in offspring.

The Opportunity

 Seeking funding for ongoing research and clinical trial.

  

Contact for more information:

Mel Larrosa
VP Business Development Healthcare
+972-2-6586692