Category LifeSciences and BioTechnology Keywords Genomics, Cancer Resistance, Species Current development stage General list: TRL3 Experimental proof of concept             Application Mutation in specific genes or variability in ...

Category LifeSciences and BioTechnology      Application Primary human hepatocytes are isolated from organs rejected from transplantation. Cells are expensive, show massive batch-to-batch variability and fail to proliferate in culture. ...

Validated approach in small animals and human cell models   Categories Ceramide, apoptosis, cancer, sphingolipids, prostate cancer Development Stage Considerable anticancer activity in vivo in prostate, colon, pancreas and melanoma mouse ...

  Application No two cancers are the same, and it can be difficult to predict which tumors are slow-growing and which are likely to grow and spread to other parts of the body. Current medical society guidelines rely on cancer stage to determine ...

  Category Medical Sciences, Stem cells, Small molecules Our Innovation Improved removal of PSCs may be obtained by identifying small molecules that selectively perturb crucial pathways in PSCs, and thus induce cell death in these cells ...

  Categories Diagnostics,  Research Development Stage In vitro and in-vivo proof of concept; ongoing research Patent Status US, Europe and China applications filed based on WO 2017/025968  Background Fluorescence guided surgery is currently ...

  Categories Treatment of cancer, neurodegeneration and infectious diseases. Development Stage In vitro proof of concept; in vivo POC Patent Status PCT publication number : WO2016/142948Highlights A new technology to inhibit the activity ...

A specific therapy for treating this serious disease   Categories Mastocytosis, Cancer Development Stage Proof-of-concept, preclinical Patent Status Patent Pending Market Mastocytosis, Mast Cell Leukemia, AllergiesBackground Mast cells ...

  Keywords Epigenetics, Dual-specificity, Enzymes, anti-cancer Current Development Stage TRL3 - Hypothesis testing and initial POC demonstrated Application Cancer cells lose their epigenetic checks and balances followed by unscheduled ...

Keywords Glioblastoma multiforme, regulatory networks, target genes Current development stage TRL3 - hypothesis testing and initial POC demonstrated in-vitro Application Glioblastoma multiforme (GBM) is a common, very aggressive brain ...

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  Categories Superactive High Afinity Leptin antagonist, mutein, multiple sclerosis, inflammatory bowel syndrome, rheumatoid arthritis, fibrosis, cardiovascular disease, CKD Cachexia, Osteoarthritis Development Stage (1) In vivo tests in ...

Delivery of chemically modified gluococorticoids (GC) into the tumor site by passive loading Categories Drug delivery for anticancer treatments, Glucocorticoids (GCs) Development Stage In vivo animal studies for anticancer therapy were ...