Background Increased production of soluble VEGF receptors during pregnancy is entirely attributable to induced expression of placental sFlt1-14 starting by the end of the first trimester. sFlt1-14 is the predominant VEGF-inhibiting protein ...

Background The invention brings a new modality of anti-bacterial treatment as a stand-alone therapy or combined with antibiotics The bacterial toxin MazF induces bacterial cell death by triggering downstream death pathways. The labile ...

Background Intravenous injection of some liposomal drugs, diagnostic agents, micelles and other lipid-based nanoparticles cause hypersensitivity reactions in up to 45% of patients,which appear to be initiated by the complement system (C) of ...

Background The human brain is comprised of water, proteins and lipids,  which are distributed in different regions of the brain and in various pathological states. As yet, it remains a major challenge to localize and quantify these molecules ...

Background Fluorescence guided surgery is currently clinically approved for non-specific fluorescent molecules (ICG and MB) and is therefore limited in terms of sensitivity and specificity. Most cancer targeted fluorescent molecules in ...

  Categories Cannabinoids, Drug Delivery, Novel Carrier, Oral Formulation Development Stage In-vivo proof of concept Patent Status PCT patent application filed Market Improved delivery of cannabinoids is a real need and has an increasing ...

  Categories Small molecules, anti-inflammatory treatment Development Stage In-vivo proof of concept Patent Status Patent application filed Market Inflammation indications: acute pancreatitis, acute live damage, fatty liver damage, ...

  Categories Cannabinoid Administration, Formulation, Drug Delivery, Novel Carriers, Transdermal Formulation, Nasal Formulation, Oral formulation Development Stage In-vivo proof of concept Patent Status Several patent applications – new ...

Oral Dosage Form for Immediate and Prolonged Action of Cannabinoids     Categories  Cannabinoids, Drug Delivery, Novel Carrier, Oral Formulation Development Stage In-vivo proof of concept Patent Status PCT patent application filed Market ...

Yousef Najajreh, Al Quds University   Background A growing number of peoples worldwide are suffering from the health consequences of obesity. As for today, Only one drug is currently approved for long-treatment of obesity-the lipase ...

Prof. Yaron Ilan, Department of Human Nutrition and Metabolism and Liver Unit Hadassah Hospital Background To date, there is no effective treatment of liver diseases with the related Hepatic-Encephalopathy symptoms. It is established that ...

Background Currently there are no molecules that can directly inhibit the activity of splicing factors. We created decoy oligonucleotides that directly bind and inhibit the splicing activity of splicing factors without affecting their ...

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Background Most active pharmaceutical ingredients (APIs) are not suitable for “passive” loading into nano-liposomes. The desired concentration in the nano-liposomes is hard to achieve. Consequently, the therapeutic efficacy in humans is not ...

 Background Glioblastoma multiforme (GBM) is a common, very aggressive brain cancer with a dismal prognosis, affecting young and middle-age adults with no effective treatment. Former efforts to diagnose glioblastoma tumors and tailor personal ...

  Additional information will be provided upon request

  Additional information will be provided upon request

  Additional information will be provided upon request

  Additional information will be provided upon request

Background With continuous increase in the elderly population, many age-related health problems have become a major healthcare issue. Attenuating deleterious age-related processes taking place in multiple organs is highly desirable. Our ...