Background Epigenome editing by DNA methylation or demethylation of regulatory sequences are widely required in medicine and in biomedical research, but current technologies are non-specific and provide unpredictable effects. This technology ...

Background There is a growing demand in the field of biological drugs for improved protein expression platforms. Consequently there is a need for affordable manufacturing methods. Our Innovation A new concept of vector design that incorporates ...

  Background Mutations in specific genes or proteins variability can dramatically enhance our probability to get cancer. Similarly, genetic variability could have the opposite effect and actually protect us from cancer, other diseases and even ...

Background Age-Related Macular Degeneration (AMD) and Diabetic Retinopathy (DR) are leading causes of blindness in the Western world. Both are characterized by pathological angiogenesis in the various eye structures. With high prevalence  in  ...

Background        Many of today’s leading compounds and drugs in pipeline fail to reach clinical stages due to poor oral bioavailability. In addition, Increase in oral bioavailability leads a lower inter and intra subject variability. Our ...

Fills the gap between crystallography and optical imaging    Background Information about macromolecules is encoded in their shape and the way they are assembled. X-ray scattering methods are important tools for investigating the structure and ...

Background TD-test kit is a simple modification of the standard disk-diffusion assay that allows the semi-quantitative evaluation of survival rate and killing dynamics of Bacteria. The TDTest enables the detection of tolerant and persistent ...

  Our Innovation: Drug-eluting stents (DES) are widely used in intravascular intervention. The current technology is based on crystallization of drug onto stent surface (with no- polymer) Coating process is resulting in high yield coatings that ...

Background One of the main obstacles for successful cryopreservation of cells is the irreversible damage to cells organelles and membranes caused by uncontrolled growth of ice in super-cooled liquid. This has a crucial impact on organ, embryo, ...

Background Valproic acid (VPA) is a first line antiepileptic and CNS drug (Epilepsy, neuropathic pain, bipolar disorders etc) Multivalent action of VPA is highly advantageous, promising improved efficacy with reduced side effects for ...

  Background Primary human hepatocytes are isolated from organs rejected from transplantation. Cells are expensive, show massive batch-to-batch variability and fail to proliferate in culture. Hepatocytes are routinely used by the pharmaceutical ...

Background One of the key problems facing the tampons industry is the fact that all too often, used tampons are flushed down the toilet. Contrary to toilet paper, tampons do not disintegrate in water. As a matter of fact, they are designed to do ...

Background  A new technology to treat various skin inflammations, irritations and infections, in which iodine (in its molecular form) being encapsulated within vesicles of approximately 100nm, is delivered deep into the skin. The uniqueness of ...

  Background Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is characterized by chronic relapsing intestinal inflammation. To date several biomarkers are used for the diagnosis of IBD, such as CRP (blood) and ...

Background Existing personal glucose levels are still controlled invasively by blood sampling. The option of constant 24 hour monitoring of blood glucose levels would significantly impact the wellbeing of diabetic patients and reduce the ever ...

  Background Malaria is caused by unicellular Plasmodium parasites which are transmitted by the bite of mosquitoes. Although several medicines are available for prophylaxis and treatment of acute infection, their application is severely hampered ...

  Current Development Stage TRL 9 Ready for mass production   Our Innovation Pouch drug delivery system (web- like films) for dermal, transdermal and nail  administration of drugs and actives for various treatments Applied to the nail or ...

Background Existing tubal ligation techniques are irreversible and have severe drawbacks.  In case of an arising need to terminate an occlusion, the implications are risky and might be traumatic. Our Innovation Novel “soluble on-demand” ...

  The technology enables an affordable and easily deployable method for detection of water/soil contamination, and/or rapid detection of viruses in humans and animals. The  method  employs the extension of the isothermal rolling circle ...

  Background Existing methods for removing potentially tumorigenic residual pluripotent stem cells (PSCs) from differentiated cultures are based on either genetic manipulations or on cell sorting. Such processes are generally not suitable for ...