Background  Micro-emulsions are formed more or less spontaneously when their components are brought into contact.  They have been the only successful delivery systems for certain types of pharmaceutical compounds, particularly compounds such as ...

Background Current preclinical and clinical data indicate that there is negligible release of drug from circulating liposomes. Once liposomes extravagate to extracellular tissue fluids, little is known of the processes determining drug release. ...

Background In the brain, α-Synuclein (α-Syn) protein is associated with the pathogenesis and progression of Parkinson’s disease and the related synucleinopathies, neurodegenerative diseases characterised by the abnormal accumulation of ...

    Background The process of cancer metastasis consists of a series of sequential events that requires deregulated proliferation and eventually distal dissemination involving detachment from the extracellular matrices and invasion of the ...

Background Epigenome editing by DNA methylation or demethylation of regulatory sequences are widely required in medicine and in biomedical research, but current technologies are non-specific and provide unpredictable effects. This technology ...

Background There is a growing demand in the field of biological drugs for improved protein expression platforms. Consequently there is a need for affordable manufacturing methods. Our Innovation A new concept of vector design that incorporates ...

  Background Mutations in specific genes or proteins variability can dramatically enhance our probability to get cancer. Similarly, genetic variability could have the opposite effect and actually protect us from cancer, other diseases and even ...

Background Age-Related Macular Degeneration (AMD) and Diabetic Retinopathy (DR) are leading causes of blindness in the Western world. Both are characterized by pathological angiogenesis in the various eye structures. With high prevalence  in  ...

Background        Many of today’s leading compounds and drugs in pipeline fail to reach clinical stages due to poor oral bioavailability. In addition, Increase in oral bioavailability leads a lower inter and intra subject variability. Our ...

  Background Neuro-protective drugs products of all types protect the brain and peripheral nervous system neurons from degeneration and injury by promoting neuronal survival, proliferation and differentiation. These products can be used in the ...

Fills the gap between crystallography and optical imaging    Background Information about macromolecules is encoded in their shape and the way they are assembled. X-ray scattering methods are important tools for investigating the structure and ...

  Background Activity against non-enveloped virusesHands transmission of viruses an important factor in the occurrence of respiratory and enteric diseases. Transfer of virus can occur to and from hands, as well as between hands and fomites. ...

Background TD-test kit is a simple modification of the standard disk-diffusion assay that allows the semi-quantitative evaluation of survival rate and killing dynamics of Bacteria. The TDTest enables the detection of tolerant and persistent ...

  Our Innovation: Drug-eluting stents (DES) are widely used in intravascular intervention. The current technology is based on crystallization of drug onto stent surface (with no- polymer) Coating process is resulting in high yield coatings that ...

Background One of the main obstacles for successful cryopreservation of cells is the irreversible damage to cells organelles and membranes caused by uncontrolled growth of ice in super-cooled liquid. This has a crucial impact on organ, embryo, ...

Background Valproic acid (VPA) is a first line antiepileptic and CNS drug (Epilepsy, neuropathic pain, bipolar disorders etc) Multivalent action of VPA is highly advantageous, promising improved efficacy with reduced side effects for ...

  Background Primary human hepatocytes are isolated from organs rejected from transplantation. Cells are expensive, show massive batch-to-batch variability and fail to proliferate in culture. Hepatocytes are routinely used by the pharmaceutical ...

Background Our invention is a new method for the successful synthesis of Multi-phosphorylated peptides that applies different coupling protocols and paves the way for the efficient and routine synthesis of multi-phosphorylated peptides of ...

Background One of the key problems facing the tampons industry is the fact that all too often, used tampons are flushed down the toilet. Contrary to toilet paper, tampons do not disintegrate in water. As a matter of fact, they are designed to do ...

Background Asthma is the most severe among the chronic allergic diseases since it can eventually lead to death. Public attention in the developed world has recently focused on asthma because of its rapidly increasing prevalence.  Currently, ...