Keywords cell free DNA diagnosis, liquid biopsies, methylation patterns, histone modification Current development stage   TRL3 - hypothesis testing and intial POC demonstrated in limited # of in-vitro modelsApplication The existing sequence ...

Keywords Medical Devices, Drug Delivery, Respiratory System Current development stage Proof-of- Concept and a demonstration designed. A prototype suitable for mass production may be produced within 12 months. Application Spinal cord ...

Background The standard MRI approach requires large magnetic fields, yielding bulky and expensive machines. Moreover, the inductive measurement is limited in terms of sensitivity and resolution. These downsides result in limited availability ...

Background Conventional manufacturing of pharmaceutical dosage forms (e.g. tablets, capsules) are typically restricted to certain designs and materials and are commonly being used in a generic form of tablets or capsules with or without enteric ...

Application Bacteria communicate and coordinate population behavior through the mechanism of quorum sensing (QS), which controls the expression of genes that affect a variety of bacterial processes. Cannabis, Cannabinoids and ...

Novel Endourethral Catheter that Allows Men to Drain Bladders Mechanically  Keywords Urology, catheter, Current development stage   TRL4 - PoC&Safety of candidate device or system is demonstrated in a defined lab or animal ...

  Background It was recently shown that enhanced expression of NAF-1, is associated with different cancers, including breast, prostate, gastric, cervical, liver, and laryngeal. Silencing of NAF-1 expression in breast, or gastric, cancer cells ...

Keywords Nanoparticles, Neuropeptides, Intranasal delivery Current development stage TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal model Highlights Emulsification in aqueous media is not effective ...

  Category Life Sciences and Biotechnology    Keywords Liver, RNA, miRNA Current development stage TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal modelvvvid demonstrated in  defined animal ...

Category Life Sciences and Bio Technology    Keywords Iterative Stochastic Elimination (ISE), Ligands, TLRs Current development stage TRL3 - hypothesis testing and intial POC demonstrated in limited # of in-vitro ...

Category Chemistry & Materials    Keywords VPA, Epilepsy, Neuropathic Pain and Bipolar Disorder Current development stage TRL 4, POC demonstrated, anticonvulsant activity tested in animal modelsApplication Prolonged epileptic ...

  Category Life Sciences and Biotechnology    Keywords Bipolar disease, Migraine, Schizophrenia, Epilepsy & Neuropathic Pain, antiepileptics, drugs (AEDs), CNS drugs Current development stage TRL7- Phase 2 clinical trials ...

Dr. Yaacov Rozenman, Head of Shaarei Tzedek’s Ophthalmology Department Background A cataract pathology causes the partial or entire lens clouding inside the eye, resulting in blurred or distorted vision. Cataract retrieval surgery is one of the ...

  Category Life Sciences and Biotechnology    Keywords Cathespin, Molecular Imaging, Cancer, CT, Computed Tomography, Current development stage TRL3 - Hypothesis testing and initial POC demonstrated in-vivo Application X-ray computed ...

  Our Innovation   Based on a provocative working hypothesis, we most probably identified the molecular origin of insulin resistance (IR). Systemic IR is induced via post-translational modification (PTM) of liver key regulatory proteins. We ...

Dr. Sharon Merims, Hadassah Medical Center   Background Many of the anti-neoplastic tyrosine kinase inhibitors are associated with prominent and sometimes dose-limiting dermatologic complications. Of severe clinical implication are the specific ...

Background Natural killer (NK) cells are innate effector lymphocytes that efficiently kill tumor cells without prior stimulation. NK are crucial first responders to tumor transformation and viral, bacterial, or fungal infections. They are also ...

  Category Life Sciences and Bio Technology    Keywords Nanoparticles, Neuropeptides, Intranasal delivery Current development stage TRL4 - POC & Safety of candidate drug formulation is demonstrated in defined animal modelHighlights ...

Category Life Sciences and Bio Technology    Keywords Chemotherapy, Drug resistance * The project is conducted in collaboration with Memorial Sloan-Kettering Cancer Center. Application Cells with multidrug resistance (MDR) due to aberrant ...

      Our Innovation We found and patented that approved drugs enhance the expression of NKp30 ligand. The upregulation is persistent and does not affect cell viability. We suggest to use this new modality as a combination therapy to improve ...