Background   Considerable efforts have been invested in recent years in developing new, effective, yet less toxic drugs for targeted cancer therapy. Currently, this diverse group of drugs includes monoclonal antibodies, immunomodulators, ...

Background The physical size of protein drugs and their susceptibility to degradation are key determinates that make them more dependent on drug delivery technologies. However formulating protein delivery systems so that they maintain their ...

Background Synthetic biology is the discipline of engineering application-driven biological functionalities that were not evolved by nature. Early breakthroughs of cell engineering, which were based on ectopic (over)expression of single sets of ...

  https://elsc.huji.ac.il/faculty-staff/yosef-grodzinsky   Background Language disorders affect up to 5% of all children and account for close to 20% of children with disabilities who receive special education. Language disorders make ...

Background The ability to control the shape, size and crystalline state of CaCO3 is significant for several industries including: Powder additives- improved flow properties (spherical shape versus irregular) of ink material, rubber filler, and ...

Our innovation: Neuropathic pain- One of our distinctive results which we optimized recently identifies several compounds that we identified as having a potential protective role in neuropathic pain. We pursued this finding in collaboration with ...

Background Obesity is the leading cause of death in America, and is associated with an increase in chronic diseases like, cardiovascular diseases, hypertension, and metabolic disease involving the liver as well as type 2 diabetes. A recent study ...

Background The therapeutic activity of most anticancer drugs in clinical use is limited by their general toxicity to proliferating cells, including some normal cells. Although chemists continue to develop novel cytotoxic agents with unique ...

A novel and personalized method for identifying the optimal anti-cancer treatment, through simultaneous detection of unique tumor sensitivities to multiple drugs or drug combinations in a multiplex manner, (this can be done) in vitro on cancer ...

Background Recurrent miscarriage, preeclampsia and intra-uterine growth restriction (IUGR) are three common implantation (placental)-related diseases and a major cause of mortality and morbidity for mother and child, complicating between 3 to 10 ...

  Background Non-alcoholic fatty liver disease (NAFLD) and associated diseases Non-alcoholic steatohepatitis (NASH), Cirrhosis, and Hepatocellular carcinoma (HCC) cost the US economy an estimated at $103 billion per year. Lipotoxicity is a major ...

Background Experimental archaeology is a field of research that studies ancient cultures by trying to reconstruct ancient lifestyles. Extensive evidence of wine and beer production in Egypt, Mesopotamia, and the Near East as early as the mid-4th ...

Background PCR using bisulfite-treated DNA as a template, which is  followed by next generation sequencing (NGS), has a major potential as a diagnostic tool, by identifying DNA derived from specific tissue based on cell type-specific methylation ...

Background        Chicken embryonic fibroblasts (CEFs) are commonly used for the production of vaccines and are a source material for cultured meat. Fibroblasts are contact-dependent limiting their large-scale production to carrier beads capable ...

Categories: Life Science & Biotechnology Technology Keywords: Nasal administration, CNS active oil,  neurodegenerative diseases, CNS Development Stage: Formulation and experiments in animals Patent Status: US  patent application ...

  Highlights: CBD is a highly lipophilic molecule   and therefore the preparation of cannabinoid-containing non- alcoholic beverages requires in general the use of various and important concentrations of additives.  We found a new technology ...

Categories: Life sciences and Biotechnology Technology Keywords: Drug Development, PPARD, Obesity, Glycogen Preserving, Lipid Metabolism, Wound Healing Development Stage: In silico, Identification of lead molecules, in vitro ...

Background Parkinson’s Disease (PD) is a progressive neurodegenerative disease caused by the loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc). As the disease progresses the number of dopaminergic neurons decreases. ...

Prof. Levy-Lahad Ephrat – Director of the Medical Genetics Institute at Shaare Zedek Hospital, Jerusalem Background Breast cancer is the most common cancer among women. In >70% of cases with suspected hereditary, no mutations could be found ...

Background Multiple strategies exist for the targeted treatment of different cell pathologies. One ongoing challenge is the introduction of therapeutic molecules into cells. Current approaches rely on viral vectors, electroporation, or carriers. ...