Nir-Paz Ran, Hadassah Medical Center Background The World Health Organization has announced antibiotic resistance is one of the biggest threats to global health, food security and development today. Up to 50% of infections in G7 countries may be ...

Cannabinoid-Based Drugs for Preventing Age-Related Osteoarthritis Mona Dvir Ginzberg   Degenerative diseases become prominent with progressive ageing and thus present the most urgent biomedical challenge facing developed countries to date. One ...

  Category LifeSciences and BioTechnology    Keywords Pain, Opioid receptor, Addiction, Opioid addiction, Narcotics, AnalgesiaApplication Severe, high-impact chronic pain affects 20 million people in the US annually, and presents a common, ...

  Background Current methods of tissue fixation leave much to be desired, essentially relying on technologies developed from the clothing and carpentry industries i.e. sutures, screws, and pins. Bioadhesives offer a less traumatic method of ...

  Background Neutrophils are potent effector cells in a wide number of infectious, inflammatory and cancerous conditions. Modulation of Neutrophil functions in these conditions may have significant therapeutic benefits and effects on disease ...

  Background Solid tumors are known to continually form hypoxic microenvironments because the proliferating tumor cells grow faster than they can attract blood vessels towards them. In hypoxic microenvironments, where there is a lack of oxygen, ...

Background To date, clinical tests that assess the level of malignancies from patient biopsies rely almost inclusively on histological analysis for specific markers and morphological cues as well as on genetic data i.e mutation analysis. In ...

  Cancer research is moving into the frontiers of how to assign the correct drug(s) to a given patient. Cancer clinicians and researchers commonly search for overexpression of oncogenic biomarkers to assign a targeted treatment, but lack ...

Background   Considerable efforts have been invested in recent years in developing new, effective, yet less toxic drugs for targeted cancer therapy. Currently, this diverse group of drugs includes monoclonal antibodies, immunomodulators, ...

Background The physical size of protein drugs and their susceptibility to degradation are key determinates that make them more dependent on drug delivery technologies. However formulating protein delivery systems so that they maintain their ...

Synthetic biology is the discipline of engineering application-driven biological functionalities that were not evolved by nature. Early breakthroughs of cell engineering, which were based on ectopic (over)expression of single sets of transgenes, ...

Background We have developed a new type of a compact scanning Micro-ellipsometer that operates with a spatial resolution on the sub 10-micron and over a broad spectral range. See Figure (next page). The Micro-ellipsometer can accurately ...

Cystic Fibrosis (CF) is an inherited disorder that causes severe damage to the lungs, digestive system and other organs in the body. There is no known cure for cystic fibrosis and the average life expectancy is between 42 and 50 years in the ...

Background Zeaxanthin is a carotenoid pigment that provides health benefits as a dietary anti-oxidant, and is also a preventive agent against degenerative diseases. Specifically, it is thought to inhibit the progression of age-related macular ...

Background Measurements of volatile acidity in wines can be a challenging issue in many young and aging wines. The primary acid that contributes to volatile acidity in wines is acetic acid. Its presence, above a specific threshold, indicates ...

  Category Life Sciences and Bio Technology    Keywords new contrast agent, imaging, mammography, tumor, visual detection, sentinel lymph node, liposomesApplication Liposomal formulation with a new moiety having very high loading of the ...

Background The ability to control the shape, size and crystalline state of CaCO3 is significant for several industries including: Powder additives- improved flow properties (spherical shape versus irregular) of ink material, rubber filler, and ...

Neuropathic pain- One of our distinctive results which we optimized recently identifies several compounds that we identified as having a potential protective role in neuropathic pain. We pursued this finding in collaboration with the Clinical ...

  Category Agriculture Keywords Passionfruit, Passiflora edulis, plant breeding, warm temperature flower abscission out-of-season fruit. Current development stage General list: TRL5 Technology validated in relevant ...

  Category Metabolic diseases Keywords Abdominal obesity, obesity Current development stage Pharmaceutical development: TRL2  Hypothesis Formulated        Collaboration Opportunity Sponsored Research with an option to License Research ...