Researcher interests: Research Interests
Drug addiction: finding the neural changes that underlie the development of addiction to drugs of abuse and cause relapse. Obesity and motivational eating: investigating the involvement of pathology in the reward circuitry in obesity.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Medical Neurobiology
Selected Publications
projection specific potentiation of ventral pallidal glutamatergic outputs after abstinence from cocaine (2019)|
The Journal of Neuroscience|
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cocaine dysregulates dynorphin modulation of inhibitory neurotransmission in the ventral pallidum in a cell type specific manner (2019)|
The Journal of Neuroscience|
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accumbens neuroimmune signaling and dysregulation of astrocytic glutamate transport underlie conditioned nicotine seeking behavior (2019)|
Addiction Biology|
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chronic calorie dense diet drives differences in motivated food seeking between obesity prone and resistant mice (2019)|
Addiction Biology|
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addiction like synaptic impairments in diet induced obesity (2017)|
Biological Psychiatry|
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loss of plasticity in the d2 accumbens pallidal pathway promotes cocaine seeking (2017)|
The Journal of Neuroscience|
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the direct and indirect pathways of the nucleus accumbens are not what you think (2017)|
Neuropsychopharmacology|
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glutamatergic mechanisms of comorbidity between acute stress and cocaine self administration (2016)|
Molecular Psychiatry|
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the nucleus accumbens mechanisms of addiction across drug classes reflect the importance of glutamate homeostasis (2016)|
Pharmacological Reviews|
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optogenetic inhibition of cortical afferents in the nucleus accumbens simultaneously prevents cue induced transient synaptic potentiation and cocaine seeking behavior (2016)|
Brain Structure & Function|
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