Researcher interests: Our lab is focused on uncovering the involvement of the endocannabinoid system in the pathogenesis of obesity and its metabolic complications, with therapeutic prospects for the development of an effective drug therapy.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: School of Pharmacy- Institute for Drug Research
Selected Publications
bone anabolic response in the calvaria following mild traumatic brain injury is mediated by the cannabinoid 1 receptor (2019)|
Scientific Reports|
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lower circulating endocannabinoid levels in children with autism spectrum disorder (2019)|
Molecular Autism|
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hu 671 a novel oleoyl serine derivative exhibits enhanced efficacy in reversing ovariectomy induced osteoporosis and bone marrow adiposity (2019)|
Molecules|
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prediction and experimental confirmation of novelperipheral cannabinoid 1 receptor antagonists (2019)|
Journal of Chemical Information and Modeling|
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dual inhibition of cannabinoid 1 receptor and inos attenuates obesity induced chronic kidney disease (2019)|
British Journal of Pharmacology|
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cannabis from a plant that modulates feeding behaviors toward developing selective inhibitors of the peripheral endocannabinoid system for the treatment of obesity and metabolic syndrome (2019)|
Toxins|
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wwox somatic ablation in skeletal muscles alters glucose metabolism (2019)|
Molecular metabolism|
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fri 297 trans signaling blockade induces mature onset obesity and insulin resistance in mice via suppression of pparalpha (2019)|
Journal of Hepatology|
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cannabinoid 1 receptor regulates mitochondrial dynamics and function in renal proximal tubular cells (2019)|
Diabetes, Obesity and Metabolism|
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magel2 modulates bone remodeling and mass in prader willi syndrome by affecting oleoyl serine levels and activity (2019)|
Journal of Bone and Mineral Research|
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in vivo anticancer activity of a nontoxic inert phenolato titanium complex high efficacy on solid tumors alone and combined with platinum drugs (2018)|
ChemMedChem|
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mirna 132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression (2018)|
Gut|
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modulation of renal glut2 by the cannabinoid 1 receptor implications for the treatment of diabetic nephropathy (2017)|
Journal of The American Society of Nephrology|
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