Researcher interests: Our lab is focused on uncovering the involvement of the endocannabinoid system in the pathogenesis of obesity and its metabolic complications, with therapeutic prospects for the development of an effective drug therapy.
FACULTY / SCHOOL: School of Medicine - IMRIC
Contact Business Development: Mel Larrosa

Selected Publications

alina nemerovski, chaim g pick, dan levy, dara bree, miaad bader, michal eger, Rivka Hadar, Joseph Tam, Yankel Gabet
bone anabolic response in the calvaria following mild traumatic brain injury is mediated by the cannabinoid 1 receptor (2019)| Scientific Reports| Read more
adi aran, alina nemirovski, aviad schnapp, hanoch cassuto, lola polianski, maya eylon, moria harel, nadia wattad, sigal tepper, Joseph Tam
lower circulating endocannabinoid levels in children with autism spectrum disorder (2019)| Molecular Autism| Read more
itai bab, malka attarnamdar, Raphael Mechoulam, reem smoum, saja baraghithy, Joseph Tam
hu 671 a novel oleoyl serine derivative exhibits enhanced efficacy in reversing ovariectomy induced osteoporosis and bone marrow adiposity (2019)| Molecules| Read more
Amiram Goldblum, Rivka Hadar, shayma elatawneh, shira hirsch, Joseph Tam
prediction and experimental confirmation of novelperipheral cannabinoid 1 receptor antagonists (2019)| Journal of Chemical Information and Modeling| Read more
adi drori, liad hinden, majdoleen ahmad, malliga r iyer, michal hermanedelstein, resat cinar, shiran udi, Joseph Tam
dual inhibition of cannabinoid 1 receptor and inos attenuates obesity induced chronic kidney disease (2019)| British Journal of Pharmacology| Read more
shira hirsch, Joseph Tam
cannabis from a plant that modulates feeding behaviors toward developing selective inhibitors of the peripheral endocannabinoid system for the treatment of obesity and metabolic syndrome (2019)| Toxins| Read more
eithan galun, Eran Elinav, evan g williams, jacob rachmilewitz, jonathan h axelrod, meirav pevsnerfischer, orr levkovitch, rinat abramovitch, ruedi aebersold, sharon perles, shiran udi, stefan rosejohn, tali lanton, Joseph Tam
fri 297 trans signaling blockade induces mature onset obesity and insulin resistance in mice via suppression of pparalpha (2019)| Journal of Hepatology| Read more
ibrahim knani, micheal e pacold, monther aburemaileh, muhannad aburemaileh, rami i aqeilan, rania akkawi, shiran udi, Joseph Tam
wwox somatic ablation in skeletal muscles alters glucose metabolism (2019)| Molecular metabolism| Read more
adi drori, alina nemirovski, anna permyakova, Rivka Hadar, shiran udi, Joseph Tam
cannabinoid 1 receptor regulates mitochondrial dynamics and function in renal proximal tubular cells (2019)| Diabetes, Obesity and Metabolism| Read more
adi drori, alina nemirovski, asaad gammal, christian p schaaf, itai bab, malka attarnamdar, Raphael Mechoulam, megan rech, reem smoum, Rivka Hadar, saja baraghithy, shira hirsch, Joseph Tam, varda grosstsur, Yankel Gabet, yehuda pollak, yshaia langer
magel2 modulates bone remodeling and mass in prader willi syndrome by affecting oleoyl serine levels and activity (2019)| Journal of Bone and Mineral Research| Read more
asaad gammal, edit y tshuva, Jacob Hochman, nitzan ganot, ori briaitbard, Joseph Tam
in vivo anticancer activity of a nontoxic inert phenolato titanium complex high efficacy on solid tumors alone and combined with platinum drugs (2018)| ChemMedChem| Read more
ben efron, david s greenberg, eleni kotsiliti, estelle r bennett, eyal shteyer, geula hanin, Mathias Heikenwalder, nadav yayon, Orit Pappo, Eli Pikarsky, rivka zangen, rotem haviv, shiran udi, Hermona Soreq, Joseph Tam, yoganathan r krishnamoorthy, yonat tzur
mirna 132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression (2018)| Gut| Read more
adi drori, alina nemirovski, anna permyakova, asaad gammal, gil leibowitz, liad hinden, matan geron, Merav Cohen, Yaakov Nahmias, Avi Priel, Rivka Hadar, sabina tsytkinkirschenzweig, saja baraghithy, shiran udi, Joseph Tam, Yael Riahi
modulation of renal glut2 by the cannabinoid 1 receptor implications for the treatment of diabetic nephropathy (2017)| Journal of The American Society of Nephrology| Read more

Contact for more information:

Mel Larrosa
VP Business Development Healthcare
+972-2-6586692
Contact ME: