Researcher interests: The molecular mechanisms governing ubiquitination and Ubl-conjugation to cellular proteins.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Biochemistry and Molecular Biology
Selected Publications
closing the gap of ubiquitin activation (2019)|
Proceedings of the National Academy of Sciences of the United States of America|
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a direct interaction between survivin and myosin ii is required for cytokinesis (2019)|
Journal of Cell Science|
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an n terminal extension to uba5 adenylation domain boosts ufm1 activation isoform specific differences in ubiquitin like protein activation (2019)|
Journal of Molecular Biology|
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assays for dissecting the in vitro enzymatic activity of yeast ubc7 (2019)|
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e1 enzyme for ubiquitin like protein activation in complex with ubl (2018)|
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e1 enzyme for ubiquitin like protein activation (2018)|
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a sub population of group a streptococcus elicits a population wide production of bacteriocins to establish dominance in the host (2018)|
Cell Host & Microbe|
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trans binding of ufm1 to uba5 stimulates uba5 homodimerization and atp binding (2018)|
The FASEB Journal|
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novel insights into the interaction of uba5 with ufm1 via a ufm1 interacting sequence (2017)|
Scientific Reports|
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ubiquitylation dependent oligomerization regulates activity of nedd4 ligases (2017)|
The EMBO Journal|
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