Researcher interests: Computational biology: transcriptional regulation, genomics, computational epigenomics and chromatin. Machine learning and algorithms.
FACULTY / SCHOOL: School of Computer Science and Engineering
DEPARTMENT: Computer Science
Selected Publications
gene activation and repression by the glucocorticoid receptor are mediated by sequestering ep300 and two modes of chromatin binding (2019)|
bioRxiv|
Read more
genomic retargeting of tumor suppressors p53 and ctcf promotes oncogenesis (2019)|
bioRxiv|
Read more
chip seq of plasma cell free nucleosomes identifies cell of origin gene expression programs (2019)|
bioRxiv|
Read more
direct induction of the three pre implantation blastocyst cell types from fibroblasts (2019)|
Cell Stem Cell|
Read more
functional characterization of the zeb2 regulatory landscape (2018)|
Human Molecular Genetics|
Read more
comprehensive human cell type methylation atlas reveals origins of circulating cell free dna in health and disease (2018)|
Nature Communications|
Read more
comprehensive human cell type methylation atlas reveals origins of circulating cell free dna in health and disease (2018)|
Nature Communications|
Read more
unraveling the transcriptional regulation of twist1 in limb development (2018)|
PLOS Genetics|
Read more
reconstructing spatial organizations of chromosomes through manifold learning (2018)|
Nucleic Acids Research|
Read more
enhancer identification using transfer and adversarial deep learning of dna sequences (2018)|
bioRxiv|
Read more
post transcriptional 3 utr cleavage of mrna transcripts generates thousands of stable uncapped autonomous rna fragments (2017)|
Nature Communications|
Read more
a hyperdynamic h3 3 nucleosome marks promoter regions in pluripotent embryonic stem cells (2017)|
Nucleic Acids Research|
Read more