Researcher interests: Investigating the transcriptional responses to RTK signaling
Signaling mediated by Receptor tyrosine kinases (RTK) often leads to changes in gene expression. Accordingly, nuclear factors that are directly phosphorylated by MAPK play key roles in interpre
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Developmental Biology and Cancer Research
Selected Publications
capicua controls toll il 1 signaling targets independently of rtk regulation (2018)|
Proceedings of the National Academy of Sciences of the United States of America|
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novel interplay between jnk and egfr signaling in drosophila dorsal closure (2017)|
PLOS Genetics|
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ras ndash erk signaling induces phosphorylation of human tle1 and downregulates its repressor function (2017)|
Oncogene|
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high throughput in vitro identification of direct mapk erk substrates (2017)|
Methods of Molecular Biology|
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phosphorylated groucho delays differentiation in the follicle stem cell lineage by providing a molecular memory of egfr signaling in the niche (2016)|
Development|
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drosophila spidey kar regulates oenocyte growth via pi3 kinase signaling (2016)|
PLOS Genetics|
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origins of context dependent gene repression by capicua (2015)|
PLOS Genetics|
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rtk signaling modulates the dorsal gradient (2012)|
Development|
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phosphorylation of the drosophila melanogaster rna binding protein how by mapk erk enhances its dimerization and activity (2012)|
PLOS Genetics|
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the capicua repressor a general sensor of rtk signaling in development and disease (2012)|
Journal of Cell Science|
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