Researcher interests: My research centers on reproduction in the dairy cow. I focus on the two major stresses affecting reproduction and fertitliy of cows - environmental heat stress and pathogenic stress. Regarding heat stress, we characterized impairments of follicular and luteal functions related to steroidogeneis, attenuation of follicular dominance and other preovulatory follicle-related functions. Regarding subclinical, chronic mastitis, we found that 1/3 of mastitic cows exhibited delayed ovulation. This syndrome involves disruption of follicular steroidogeneis, low gene expression in theca and granulosa cells and low and delayed LH surge. Attepts to improve fertility of subclinical mastitic cows are currently examined. We found that small early antral follicles are susceptible to long-term, exposure to minimal doses of both Gram-positive and Gram-negative toxins, and the induced damage is then carried over to the preovulatory follicles, corresponding well with the long-term chronic nature of subclinical mastitis. We also found lack of association between clinical mastitic events and premature induction of luteal regression, suggesting that the main cause of low fertility caused by E. coli mastitis post-AI is directed at the embryo rather than the corpus luteum.
DEPARTMENT: Animal Sciences
Contact Business Development: Ilya Pittel

Selected Publications

ayala dvir, d kalo, d wolfenson, gabriel leitner, ori furman, David Wolfenson, y lavon, z roth
oocyte maturation in plasma or follicular fluid obtained from lipopolysaccharide treated cows disrupts its developmental competence (2020)| Theriogenology| Read more
d wolfenson, e ezra, gabriel leitner, David Wolfenson, y kressel, y lavon
comparing effects of bovine streptococcus and escherichia coli mastitis on impaired reproductive performance (2019)| Journal of Dairy Science| Read more
d wolfenson, gabriel leitner, David Wolfenson, y lavon, z roth
effects of mastitis on ovarian function and fertility in dairy cows (2019)| Bioscientifica Proceedings| Read more
d wolfenson, David Wolfenson, z roth
impact of heat stress on cow reproduction and fertility (2019)| Animal Frontiers| Read more
d wolfenson, David Wolfenson, z roth
comparing the effects of heat stress and mastitis on ovarian function in lactating cows basic and applied aspects (2016)| Domestic Animal Endocrinology| Read more
d biran, d wolfenson, e ezra, gabriel leitner, m kaim, David Wolfenson, y lavon
two approaches to improve fertility of subclinical mastitic dairy cows (2016)| Journal of Dairy Science| Read more
d kalo, d wolfenson, gabriel leitner, ori furman, s asaf, David Wolfenson, y lavon, z roth
subclinical mastitis disrupts oocyte cytoplasmic maturation in association with reduced developmental competence and impaired gene expression in preimplantation bovine embryos (2016)| Reproduction, Fertility and Development| Read more
d wolfenson, gabriel leitner, David Wolfenson, y lavon
the disruptive effects of mastitis on reproduction and fertility in dairy cows (2015)| Italian Journal of Animal Science| Read more
d reznikov, d wolfenson, e friedman, Hillary Voet, David Wolfenson, z roth
hormonal treatment before and after artificial insemination differentially improves fertility in subpopulations of dairy cows during the summer and autumn (2014)| Journal of Dairy Science| Read more
d wolfenson, gabriel leitner, ori furman, shamay jacoby, David Wolfenson, y lavon, z roth
experimental model of toxin induced subclinical mastitis and its effect on disruption of follicular function in cows (2014)| Theriogenology| Read more

Contact for more information:

Ilya Pittel
VP, BD AGTECH, FOODTECH, VETERINARY & ENVIRONMENT
+972-2-6586693
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