Researcher interests: Antigenic analysis of parasites. Host response. Parasite genetics. Ancient DNA. Bacteria isolates from amber. Genomics of the actinobacteria. Bacteria in bioremediation.
FACULTY / SCHOOL: Faculty of Science
Selected Publications
assays for dissecting the in vitro enzymatic activity of yeast ubc7 (2019)|
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the insulin igf signaling cascade modulates sumoylation to regulate aging and proteostasis in caenorhabditis elegans (2018)|
eLife|
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protein quality control degradation in the nucleus (2018)|
Annual Review of Biochemistry|
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temporal profiling of redox dependent heterogeneity in single cells (2018)|
eLife|
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from precise slicing to general shredding the ubiquitin ligase ubr1 roqs as a multipurpose protein terminator (2018)|
Molecular Cell|
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integrated proteogenomic approach for identifying degradation motifs in eukaryotic cells (2018)|
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sequential poly ubiquitylation by specialized conjugating enzymes expands the versatility of a quality control ubiquitin ligase (2016)|
Molecular Cell|
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mapping the landscape of a eukaryotic degronome (2016)|
Molecular Cell|
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degradation of ndd1 by apc c cdh1 generates a feed forward loop that times mitotic protein accumulation (2015)|
Nature Communications|
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distinct activation of an e2 ubiquitin conjugating enzyme by its cognate e3 ligases (2015)|
Proceedings of the National Academy of Sciences of the United States of America|
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the dna2 nuclease helicase is an estrogen dependent gene mutated in breast and ovarian cancers (2014)|
Oncotarget|
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