Researcher interests: Molecular mechanisms through which neurons find their targets during development and regeneration to form neural networks. Semaphorins: their role in nervous system injury.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Developmental Biology and Cancer Research
Selected Publications
human ipsc derived astrocytes from als patients with mutated c9orf72 show increased oxidative stress and neurotoxicity (2019)|
EBioMedicine|
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an approach for accelerated isolation of genetically manipulated cell clones with reduced clonal variability (2019)|
Journal of Cell Science|
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an approach for accelerated isolation of genetically manipulated cell clones with reduced clonal variability (2018)|
bioRxiv|
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combined shrna over crispr cas9 as a methodology to detect off target effects and a potential compensatory mechanism (2018)|
Scientific Reports|
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mir126 5p downregulation facilitates axon degeneration and nmj disruption via a non cell autonomous mechanism in als (2018)|
The Journal of Neuroscience|
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als related human cortical and motor neurons survival is differentially affected by sema3a (2018)|
Cell Death and Disease|
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muscles secretion of toxic factors regulated by mir126 5p facilitate motor neuron degeneration in als (2017)|
Journal of the Neurological Sciences|
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abnormalities in a to i rna editing patterns in cns injuries correlate with dynamic changes in cell type composition (2017)|
Scientific Reports|
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a new impedance based approach to test the activity of recombinant protein semaphorins as a test case (2015)|
European Journal of Cell Biology|
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astrogliosis induced by brain injury is regulated by sema4b phosphorylation (2015)|
eneuro|
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