Researcher interests: The reason that vertebrates do not look like, say, jellyfish is their skeletal system, which supports their body and protects vital organs while enabling efficient mobility. These functions depend on a precise and optimally-designed overall body proportioning determined by the size of the skeleton, which in turn is determined by the rate and duration of bone growth. Longitudinal bone growth occurs via the chondrocytes at the growth plates (GP), through a very tightly regulated process of endochondral ossification. The chondrocytes differentiate and produce cartilage anlagen (endochondral) that is sequentially calcified, degraded and replaced by bone (ossification). When the system is functioning correctly, our legs are of equal length, as are our arms. However, disrupted regulation is manifested in skeletal diseases, malformations and height disarrays.
Contact Business Development: Amichai Baron

Selected Publications

Anna Idelevich, Efrat Monsonego-Ornan, Yoach Rais
Bone Gla Protein Increases HIF-1α–Dependent Glucose Metabolism and Induces Cartilage and Vascular Calcification (2011)| ATVB| Read more
Elazar Zelzer, Efrat Monsonego-Ornan, Ron Shahar, Stefanie Krauss
Mechanical Function of a Complex Three‐Dimensional Suture Joining the Bony Elements in the Shell of the Red‐Eared Slider Turtle (2008)| Wiley Online Library | Read more
Adi Reich, Amnon Sharir, Efrat Monsonego-Ornan, Ron Shahar
The effect of weight loading and subsequent release from loading on the postnatal skeleton (2008)| ScienceDirect| Read more

Contact for more information:

Amichai Baron
VP, Head of Business Development, Agritech & Envir
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