Researcher interests: Nucleic acid chemistry; peptide chemistry. The synthesis of chemically- modified siRNA and miRNA as therapeutic molecules. Strategies for efficient and sequence-specific DNA and RNA modifying agents. Peptide Nucleic Acid (PNA)-based molecular beacons developed as novel diagnostic tools for detecting endogenous RNA in cells and human biopsies. The potential therapeutic use of PNAs as antimalarial agents.
FACULTY / SCHOOL: School of Medicine - IMRIC

Selected Publications

ahlam barhoum, Rami Aqeilan, kyle kurek, lina jaber, Marco Galasso, omer, rania akkawi, saleh khawaled, vadim maximov, Eylon Yavin , Zaidoun Salah
mir 16 1 3p and mir 16 2 3p possess strong tumor suppressive and anti metastatic properties in osteosarcoma (2019)| International Journal of Cancer| Read more
antoine clery, erez levanon, frederic allain, georgina barnabas, gil levkowitz, Jakob Biran, Rotem Karni, maxim mogilevsky, miri danangotthold, odelia shimshon, polina denichenko, saran kumar, Tamar Geiger, thomas welte, Eylon Yavin
specific inhibition of splicing factor activity by decoy rna oligonucleotides (2019)| Nature Communications| Read more
adi mogilevsky, florian heyd, Rotem Karni, Eli Keshet, maxim mogilevsky, odelia shimshon, saran kumar, Eylon Yavin
modulation of mknk2 alternative splicing by splice switching oligonucleotides as a novel approach for glioblastoma treatment (2018)| Nucleic Acids Research| Read more
adva krivitsky, anat eldarboock, dikla benshushan, eilam yeini, eytan ruppin, Gadi Cohen, galia tiram, jack henkin, joo sang lee, Philip Lazarovici, marcelo calderon, michael milyavsky, nava almog, orit amsalem, paula ofek, rachel grossman, rainer haag, roni blatt, ronit satchifainaro, shiran ferber, Eylon Yavin , zvi ram
reverting the molecular fingerprint of tumor dormancy as a therapeutic strategy for glioblastoma (2018)| The FASEB Journal| Read more
dana grunhaus, Assaf FRIEDLER, odelia shimshon, ofrah faust, Eylon Yavin
protein regulation by intrinsically disordered regions a role for subdomains in the idr of the hiv 1 rev protein (2018)| ChemBioChem| Read more
itamar peled, Eylon Yavin
predictive model for the sequence dependent fluorogenic response of forced intercalation peptide nucleic acid (2018)| ACS Omega| Read more
Rotem Karni, maxim mogilevsky, terese soudah, Eylon Yavin
clip6 pna peptide conjugates non endosomal delivery of splice switching oligonucleotides (2017)| Bioconjugate Chemistry| Read more
Aviram Nissan, dovrat brass, ilana ariel, meital bloch, ron kenett, Abraham Rubinstein, Eylon Yavin
the effect of linker type and recognition peptide conjugation chemistry on tissue affinity and cytotoxicity of charged polyacrylamide (2017)| Journal of Controlled Release| Read more
Simon Benita, Philip Lazarovici, orit amsalem, sandrine benhamron, taher nassar, Eylon Yavin
solid nano in nanoparticles for potential delivery of sirna (2017)| Journal of Controlled Release| Read more
andreas ingemann jensen, Yechezkel Barenholz, keren turjeman, kirill makedonski, noga yerushalmi, rivka cohen, sharon avkinnachum, tirtsa kleinman, Eylon Yavin
lipid assemblies and uses thereof and some ph and electrostatic modulating lipids to be used in said assemblies (2016)| | Read more
hashoul, netanel kolevzon, Abraham Rubinstein, Shankar Naik, Eylon Yavin
single point mutation detection in living cancer cells by far red emitting pna fit probes (2016)| Chemical Communications| Read more
lauren jablonowski, margaret wheatley, meital bloch, ron kenett, Abraham Rubinstein, Eylon Yavin
a multifactorial analysis of complex pharmaceutical platforms an application of design of experiments to targetable polyacrylamide and ultrasound contrast agents (2015)| Polymers for Advanced Technologies| Read more
Ron Dzikowski, guy pozner, inbar amitavraham, netanel kolevzon, shiri eshar, yair fastman, Eylon Yavin
antisense long noncoding rnas regulate var gene activation in the malaria parasite plasmodium falciparum (2015)| Proceedings of the National Academy of Sciences of the United States of America| Read more
Abraham Nyska, dorit moradov, irena djavsarov, lauren jablonowski, margaret wheatley, meital bloch, Abraham Rubinstein, Eylon Yavin
multi modal detection of colon malignancy by nir tagged recognition polymers and ultrasound contrast agents (2015)| International Journal of Pharmaceutics| Read more
Ezequiel Wexselblatt, Gad Glaser, Ilana Kaspy, joshua katzhendler, Eylon Yavin
design synthesis and structure activity relationship of novel relacin analogs as inhibitors of rel proteins (2013)| European Journal of Medicinal Chemistry| Read more
Ezequiel Wexselblatt, Gad Glaser, Ilana Kaspy, joshua katzhendler, nir london, ora schuelerfurman, sigal benyehuda, yaara oppenheimershaanan, Eylon Yavin
relacin a novel antibacterial agent targeting the stringent response (2012)| PLOS Pathogens| Read more
miriam shmuel, netanel kolevzon, Israel Ringel, sandrine benhamron, uriel kuflik, Eylon Yavin
multiple triphenylphosphonium cations as a platform for the delivery of a pro apoptotic peptide (2011)| Pharmaceutical Research| Read more

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