Researcher interests: Nucleic acid chemistry; peptide chemistry. The synthesis of chemically- modified siRNA and miRNA as therapeutic molecules. Strategies for efficient and sequence-specific DNA and RNA modifying agents. Peptide Nucleic Acid (PNA)-based molecular beacons developed as novel diagnostic tools for detecting endogenous RNA in cells and human biopsies. The potential therapeutic use of PNAs as antimalarial agents.
FACULTY / SCHOOL: School of Medicine - IMRIC

Selected Publications

antoine clery, erez y levanon, frederic h t allain, georgina d barnabas, gil levkowitz, Jakob Biran, Rotem Karni, maxim mogilevsky, miri danangotthold, odelia shimshon, polina denichenko, saran kumar, Tamar Geiger, thomas welte, Eylon Yavin
specific inhibition of splicing factor activity by decoy rna oligonucleotides (2019)| Nature Communications| Read more
rami i aqeilan, saleh khawaled, terese soudah, Eylon Yavin
antimir 155 cyclic peptide pna conjugate synthesis cellular uptake and biological activity (2019)| ACS Omega| Read more
Aviram Nissan, dina hashoul, maria falchenko, odelia tepper, rachel shapira, vera paviov, Eylon Yavin
red emitting fit pnas on site detection of rna biomarkers in fresh human cancer tissues (2019)| Biosensors and Bioelectronics| Read more
ahlam barhoum, kyle c kurek, lina jaber, Marco Galasso, omer or, rami i aqeilan, rania akkawi, saleh khawaled, vadim v maximov, Eylon Yavin , Zaidoun Salah
mir 16 1 3p and mir 16 2 3p possess strong tumor suppressive and antimetastatic properties in osteosarcoma (2019)| International Journal of Cancer| Read more
ahlam barhoum, kyle c kurek, lina jaber, Marco Galasso, omer or, rami i aqeilan, rania akkawi, saleh khawaled, vadim v maximov, Eylon Yavin , Zaidoun Salah
mir 16 1 3p and mir 16 2 3p possess strong tumor suppressive and antimetastatic properties in osteosarcoma (2019)| International Journal of Cancer| Read more
adi mogilevsky, florian heyd, Rotem Karni, Eli Keshet, maxim mogilevsky, odelia shimshon, saran kumar, Eylon Yavin
modulation of mknk2 alternative splicing by splice switching oligonucleotides as a novel approach for glioblastoma treatment (2018)| Nucleic Acids Research| Read more
adva krivitsky, anat eldarboock, dikla benshushan, eilam yeini, eytan ruppin, Gadi Cohen, galia tiram, jack henkin, joo sang lee, marcelo calderon, michael milyavsky, nava almog, orit amsalem, paula ofek, philip lazarovici, rachel grossman, rainer haag, roni blatt, ronit satchifainaro, shiran ferber, Eylon Yavin , zvi ram
reverting the molecular fingerprint of tumor dormancy as a therapeutic strategy for glioblastoma (2018)| The FASEB Journal| Read more
dana grunhaus, Assaf FRIEDLER, odelia shimshon, ofrah faust, Eylon Yavin
protein regulation by intrinsically disordered regions a role for subdomains in the idr of the hiv 1 rev protein (2018)| ChemBioChem| Read more
itamar peled, Eylon Yavin
predictive model for the sequence dependent fluorogenic response of forced intercalation peptide nucleic acid (2018)| ACS Omega| Read more
Simon Benita, orit amsalem, philip lazarovici, sandrine benhamron, taher nassar, Eylon Yavin
solid nano in nanoparticles for potential delivery of sirna (2017)| Journal of Controlled Release| Read more
Aviram Nissan, dovrat brass, ilana ariel, meital bloch, ron s kenett, Abraham Rubinstein, Eylon Yavin
the effect of linker type and recognition peptide conjugation chemistry on tissue affinity and cytotoxicity of charged polyacrylamide (2017)| Journal of Controlled Release| Read more
d hashoul, netanel kolevzon, Abraham Rubinstein, Shankar Naik, Eylon Yavin
single point mutation detection in living cancer cells by far red emitting pna fit probes (2016)| Chemical Communications| Read more
lauren j jablonowski, margaret a wheatley, meital bloch, ron s kenett, Abraham Rubinstein, Eylon Yavin
a multifactorial analysis of complex pharmaceutical platforms an application of design of experiments to targetable polyacrylamide and ultrasound contrast agents (2015)| Polymers for Advanced Technologies| Read more
Abraham Nyska, dorit moradov, irena djavsarov, lauren j jablonowski, margaret a wheatley, meital bloch, Abraham Rubinstein, Eylon Yavin
multi modal detection of colon malignancy by nir tagged recognition polymers and ultrasound contrast agents (2015)| International Journal of Pharmaceutics| Read more

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