Researcher interests: subcellular targeting, translocation across membranes, folding and subcellular distribution of proteins in yeast as a model for eukaryotic cells.phenomena of dual targeting and localization of proteins.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Microbiology and Molecular Genetics
Selected Publications
a combination of two novel vars2 variants causes a mitochondrial disorder associated with failure to thrive and pulmonary hypertension (2019)|
Journal of Molecular Medicine|
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author correction genome wide swap tag yeast libraries for proteome exploration (2019)|
Nature Methods|
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genome wide swap tag yeast libraries for proteome exploration (2018)|
Nature Methods|
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bacterial fumarase and l malic acid are evolutionary ancient components of the dna damage response (2017)|
eLife|
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author response bacterial fumarase and l malic acid are evolutionary ancient components of the dna damage response (2017)|
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homozygous mutation p pro304his in idh3a encoding isocitrate dehydrogenase subunit is associated with severe encephalopathy in infancy (2017)|
Neurogenetics|
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detection of dual targeting and dual function of mitochondrial proteins in yeast (2017)|
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cytosolic hsp60 can modulate proteasome activity in yeast (2015)|
Journal of Biological Chemistry|
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evolving dual targeting of a prokaryotic protein in yeast (2013)|
Molecular Biology and Evolution|
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fumarase a mitochondrial metabolic enzyme and a cytosolic nuclear component of the dna damage response (2010)|
PLOS Biology|
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organic acids old metabolites new themes (2006)|
Journal of Chemical Technology & Biotechnology|
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