Researcher interests: The effector functions of XBP-1 on the synthesis and breakdown of glycoproteins. Genes responsible for resistance to bortezomib, and their underlying mechanism of action.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: School of Pharmacy- Institute for Drug Research
Selected Publications
the integrated stress response promotes b7h6 expression (2019)|
Journal of Molecular Medicine|
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constitutive uprer activation sustains tumor cell differentiation (2019)|
bioRxiv|
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polyglutamine related aggregates serve as a potent antigen source for cross presentation by dendritic cells (2019)|
bioRxiv|
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repression of viral gene expression and replication by the unfolded protein response effector xbp1u (2019)|
bioRxiv|
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control of glioblastoma differentiated to stem cell reprogramming by ire1α xbp1s signaling (2019)|
bioRxiv|
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cathepsin l regulates metabolic networks controlling rapid cell growth and proliferation (2019)|
Molecular & Cellular Proteomics|
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constitutive ire1α signaling maintains glioblastoma cell differentiation (2019)|
bioRxiv|
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low concentrations of cadmium chloride promotes protein translation and improve cell line productivity (2019)|
Biotechnology and Bioengineering|
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transcription of the nkg2d ligand mica is suppressed by the ire1 xbp1 pathway of the unfolded protein response through the regulation of e2f1 (2019)|
The FASEB Journal|
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ire1 ube2d3 signaling controls the recruitment of myeloid cells to glioblastoma (2019)|
bioRxiv|
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mtorc1 activation in b cells confers impairment of marginal zone microarchitecture by exaggerating cathepsin activity (2018)|
Immunology|
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increasing the affinity of cationized polyacrylamide paclitaxel nanoparticles towards colon cancer cells by a surface recognition peptide (2017)|
International Journal of Pharmaceutics|
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induction of endoplasmic reticulum stress and unfolded protein response constitutes a pathogenic strategy of group a streptococcus (2014)|
Frontiers in Cellular and Infection Microbiology|
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