Researcher interests: The effector functions of XBP-1 on the synthesis and breakdown of glycoproteins. Genes responsible for resistance to bortezomib, and their underlying mechanism of action.
FACULTY / SCHOOL: School of Medicine - IMRIC

Selected Publications

akram obiedat, david e gilham, einat seidel, eric chevet, jennifer bolsee, julie taischmiedel, lorraine springuel, Ofer Mandelboim, miriam shmuel, mohamed mahameed, noam sternginossar, priya dipta, Boaz Tirosh, tony avril, yoav charpakamikam
the integrated stress response promotes b7h6 expression (2019)| Journal of Molecular Medicine| Read more
abhay pandit, afshin samali, akram obiedat, aristotelis chatziioannou, dimitrios doultsinos, eric chevet, joanna obacz, john b patterson, juhi samal, konstantinos voutetakis, mari mcmahon, pierrejean le reste, quinping zheng, raphael pineau, Boaz Tirosh, tony avril
constitutive uprer activation sustains tumor cell differentiation (2019)| bioRxiv| Read more
ami navon, caterina curato, dikla berko, rotem karmona, shira tabachnickcherny, sivan pinto, steffen jung, Boaz Tirosh, Yochai Wolf, Ziv Porat
polyglutamine related aggregates serve as a potent antigen source for cross presentation by dendritic cells (2019)| bioRxiv| Read more
eelco van anken, florian hinte, Boaz Tirosh, wolfram brune
repression of viral gene expression and replication by the unfolded protein response effector xbp1u (2019)| bioRxiv| Read more
abhay pandit, afshin samali, akram obiedat, aristotelis chatziioannou, dimitrios doultsinos, eric chevet, florence jouan, joanna obacz, john b patterson, juhi samal, konstantinos voutetakis, mari mcmahon, pierrejean le reste, quinping zheng, raphael pineau, Boaz Tirosh, tony avril
control of glioblastoma differentiated to stem cell reprogramming by ire1α xbp1s signaling (2019)| bioRxiv| Read more
adi anaki, benedikt m kessler, Galia Blum, Emmanuelle Merquiol, farnusch kaschani, gal itzhak, markus kaiser, mohamed mahameed, Boaz Tirosh, tommy weiss sadan, yael bennun, zhanru yu
cathepsin l regulates metabolic networks controlling rapid cell growth and proliferation (2019)| Molecular & Cellular Proteomics| Read more
abhay pandit, afshin samali, akram obiedat, aristotelis chatziioannou, dimitrios doultsinos, eric chevet, florence jouan, joanna obacz, john b patterson, juhi samal, konstantinos voutetakis, mari mcmahon, pierrejean le reste, quinping zheng, raphael pineau, Boaz Tirosh, tony avril
constitutive ire1α signaling maintains glioblastoma cell differentiation (2019)| bioRxiv| Read more
akram obiedat, gad beck, jeffrey c johnson, mohamed mahameed, Boaz Tirosh
low concentrations of cadmium chloride promotes protein translation and improve cell line productivity (2019)| Biotechnology and Bioengineering| Read more
akram obiedat, aristotelis chatziioannou, einat seidel, eric chevet, konstantinos voutetakis, Ofer Mandelboim, mari mcmahon, mohamed mahameed, orit berhani, pinchas tsukerman, Boaz Tirosh, tony avril
transcription of the nkg2d ligand mica is suppressed by the ire1 xbp1 pathway of the unfolded protein response through the regulation of e2f1 (2019)| The FASEB Journal| Read more
abhay pandit, akram obiedat, aristotelis chatziioannou, e vlachavas, eric chevet, florence jouan, j archambeau, j obacz, john b patterson, juhi samal, kim barroso, konstantinos voutetakis, l negroni, p j le reste, q zheng, raphael pineau, t fainsodlevi, Boaz Tirosh, tony avril, veronique quillien, z granot
ire1 ube2d3 signaling controls the recruitment of myeloid cells to glioblastoma (2019)| bioRxiv| Read more
Galia Blum, Emmanuelle Merquiol, nadine hovelmeyer, naresh kumar meena, sandrine benhamron, saran kumar, shakti prasad pattanayak, Boaz Tirosh, yael bennun
mtorc1 activation in b cells confers impairment of marginal zone microarchitecture by exaggerating cathepsin activity (2018)| Immunology| Read more
increasing the affinity of cationized polyacrylamide paclitaxel nanoparticles towards colon cancer cells by a surface recognition peptide (2017)| International Journal of Pharmaceutics| Read more
aparna anand, baruch b hertzog, cheng catherine youting, debabrata biswas, Emanuel Hanski, miriam ravins, Moshe Baruch, Boaz Tirosh
induction of endoplasmic reticulum stress and unfolded protein response constitutes a pathogenic strategy of group a streptococcus (2014)| Frontiers in Cellular and Infection Microbiology| Read more

Contact for more information:

Shani Bullock
VP, Business Development, Healthcare
+972-2-6586608
Contact ME: