Researcher interests: The molecular basis for oncogenic transformation.
FACULTY / SCHOOL: Faculty of Science

Selected Publications

adi salzberg, allan barsinai, David Engelberg, helit rozen, navit mooshayef, rotem lange, shaked barcohen, tatyana kushnir, zeev paroush
an activating mutation in erk causes hyperplastic tumors in a scribble mutant tissue in drosophila (2019)| Genetics| Read more
arie admon, dganit melamed, David Engelberg, tal goshenlago
isolation and characterization of intrinsically active mek independent mutants of mpk1 erk (2017)| Methods of Molecular Biology| Read more
David Engelberg, jonah beenstock, navit mooshayef
how do protein kinases take a selfie autophosphorylate (2016)| Trends in Biochemical Sciences| Read more
anat goldbergcarp, arie admon, chen bai, dganit melamed, David Engelberg, ilona darlyuksaadon, natalie g ahn, tal goshenlago
variants of the yeast mapk mpk1 are fully functional independently of activation loop phosphorylation (2016)| Molecular Biology of the Cell| Read more
arie admon, benjamin p garfinkel, dafna mordechay, dganit melamed, David Engelberg, jonah beenstock, natalie g ahn, navit mooshayef
p38β mitogen activated protein kinase modulates its own basal activity by autophosphorylation of the activating residue thr180 and the inhibitory residues thr241 and ser261 (2016)| Molecular and Cellular Biology| Read more
David Engelberg, jonah beenstock, Oded Livnah, masha tesker, ruchama hayouka, sadiduddin edbe selamat
tighter αc helix αl16 helix interactions seem to make p38α less prone to activation by autophosphorylation than hog1 (2016)| Bioscience Reports| Read more
Alexei Shir, anat goldbergcarp, arie admon, dganit melamed, David Engelberg, ilona darlyuksaadon, jonah beenstock, karina smorodinskyatias, Oded Livnah, natalie g ahn, navit mooshayef, tal goshenlago, yael karamansha
intrinsically active variants of erk oncogenically transform cells and disclose unexpected autophosphorylation capability that is independent of tey phosphorylation (2016)| Molecular Biology of the Cell| Read more
chen bai, David Engelberg, masha tesker
the yeast hot1 transcription factor is critical for activating a single target gene stl1 (2015)| Molecular Biology of the Cell| Read more
transmembrane signaling in saccharomyces cerevisiae as a model for signaling in metazoans state of the art after 25 years (2014)| Cellular Signalling| Read more
arie admon, dganit melamed, David Engelberg, jonah beenstock, Oded Livnah, natalie g ahn, sheer benyehuda
the p38β mitogen activated protein kinase possesses an intrinsic autophosphorylation activity generated by a short region composed of the α g helix and mapk insert (2014)| Journal of Biological Chemistry| Read more
dorin ben chetrit, David Engelberg, Oded Livnah, nadav komornik, Netanel Tzarum
def pocket in p38α facilitates substrate selectivity and mediates autophosphorylation (2013)| Journal of Biological Chemistry| Read more
conformational bias imposed by source microseeds results in structural ambiguity (2011)| Acta Crystallographica Section F-structural Biology and Crystallization Communications| Read more
active mutants of the tcr mediated p38α alternative activation site show changes in the phosphorylation lip and def site formation (2011)| Journal of Molecular Biology| Read more

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