Researcher interests: Prof. Rubinstein's research interests are focused on site-specific therapy and real-time diagnostics of inflammation and malignant processes in the gastrointestinal (GI) tract. It includes biodegradable polymers (modified polysaccharides) colon-specific drug delivery, site specific therapy of IBD by directed nano-vehicles, mechanistic understanding of affinity processes between saccharide-containing polymers and the intestinal epithelium and optimizing multimodal therapy by remotely eroding vehicles.
FACULTY / SCHOOL: School of Medicine - IMRIC

Selected Publications

racheli sharon gabbay, roberto scaffaro, ron s kenett, Abraham Rubinstein
synchronizing the release rates of salicylate and indomethacin from degradable chitosan hydrogel and its optimization by definitive screening design (2018)| European Journal of Pharmaceutical Sciences| Read more
increasing the affinity of cationized polyacrylamide paclitaxel nanoparticles towards colon cancer cells by a surface recognition peptide (2017)| International Journal of Pharmaceutics| Read more
ron s kenett, Abraham Rubinstein
generalizing research findings for enhanced reproducibility a translational medicine case study (2017)| Social Science Research Network| Read more
Aviram Nissan, dovrat brass, ilana ariel, meital bloch, ron s kenett, Abraham Rubinstein, Eylon Yavin
the effect of linker type and recognition peptide conjugation chemistry on tissue affinity and cytotoxicity of charged polyacrylamide (2017)| Journal of Controlled Release| Read more
d hashoul, netanel kolevzon, Abraham Rubinstein, Shankar Naik, Eylon Yavin
single point mutation detection in living cancer cells by far red emitting pna fit probes (2016)| Chemical Communications| Read more
lauren j jablonowski, margaret a wheatley, meital bloch, ron s kenett, Abraham Rubinstein, Eylon Yavin
a multifactorial analysis of complex pharmaceutical platforms an application of design of experiments to targetable polyacrylamide and ultrasound contrast agents (2015)| Polymers for Advanced Technologies| Read more
dorit moradov, Efrat Harel, helena shifrin, marta weinstock, mirela nadlermilbauer, morris srebnik, Abraham Rubinstein
the anti inflammatory activity of a novel fused cyclopentenone phosphonate and its potential in the local treatment of experimental colitis (2015)| Gastroenterology Research and Practice| Read more
Abraham Nyska, dorit moradov, irena djavsarov, lauren j jablonowski, margaret a wheatley, meital bloch, Abraham Rubinstein, Eylon Yavin
multi modal detection of colon malignancy by nir tagged recognition polymers and ultrasound contrast agents (2015)| International Journal of Pharmaceutics| Read more
Yechezkel Barenholz, dganit danino, hadas perlstein, peter gimeson, rivka cohen, Abraham Rubinstein, tanya turovsky
thermotropic behavior of celecoxib loaded beta casein micelles relevance to the improved bioavailability (2015)| European Journal of Nanomedicine| Read more
j stefan rokem, Michael Friedman, paula fischer, raphael radai, Abraham Rubinstein
the effect of intestinal bacteria adherence on drug diffusion through solid films under stationary conditions (1997)| Pharmaceutical Research| Read more
j stefan rokem, miriam ezra, raphael radai, Abraham Rubinstein, seema pathak
in vitro evaluation of calcium pectinate a potential colon specific drug delivery carrier (1993)| Pharmaceutical Research| Read more

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