Researcher interests: Degeneration and regeneration in the peripheral and central nervous systems. The involvement of the immune system in degeneration and regeneration in the nervous system.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Medical Neurobiology
Selected Publications
galectin 3 mac 2 controls microglia phenotype whether amoeboid and phagocytic or branched and non phagocytic by regulating the cytoskeleton (2019)|
Frontiers in Cellular Neuroscience|
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tyrphostin ag126 exerts neuroprotection in cns inflammation by a dual mechanism (2015)|
Glia|
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traumatic injury to peripheral nerves (2015)|
Nerves and Nerve Injuries
Vol 2: Pain, Treatment, Injury, Disease and Future Directions|
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phagocytic receptors activate and immune inhibitory receptor sirpα inhibits phagocytosis through paxillin and cofilin (2014)|
Frontiers in Cellular Neuroscience|
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complement receptor 3 negatively regulates the phagocytosis of degenerated myelin through tyrosine kinase syk and cofilin (2012)|
Journal of Neuroinflammation|
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myelin down regulates myelin phagocytosis by microglia and macrophages through interactions between cd47 on myelin and sirpα signal regulatory protein α on phagocytes (2011)|
Journal of Neuroinflammation|
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wallerian degeneration the innate immune response to traumatic nerve injury (2011)|
Journal of Neuroinflammation|
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cytoskeleton plays a dual role of activation and inhibition in myelin and zymosan phagocytosis by microglia (2010)|
The FASEB Journal|
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dissimilar and similar functional properties of complement receptor 3 in microglia and macrophages in combating yeast pathogens by phagocytosis (2010)|
Glia|
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the role of galectin 3 mac 2 in the activation of the innate immune function of phagocytosis in microglia in injury and disease (2009)|
Journal of Molecular Neuroscience|
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