Researcher interests: Signal transduction involving ubiquitin-mediated protein degradation.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Immunology and Cancer Research
Selected Publications
β trcp upregulates hif 1 in prostate cancer cells (2019)|
The Prostate|
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small molecules co targeting ckiα and the transcriptional kinases cdk7 9 control aml in preclinical models (2018)|
Cell|
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crystal structure of human ckidelta with a86 (2018)|
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crystal structure of human cdk9 cyclint1 with a86 (2018)|
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crystal structure of human csnk1a1 with a86 (2018)|
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casein kinase 1 epsilon or 1 delta required for wnt mediated intestinal stem cell maintenance (2017)|
The EMBO Journal|
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ck1α ablation in keratinocytes induces p53 dependent sunburn protective skin hyperpigmentation (2017)|
Proceedings of the National Academy of Sciences of the United States of America|
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cancer cell autonomous parainflammation mimics immune cell infiltration (2017)|
Cancer Research|
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792 ck1α ablation in keratinocytes induces p53 dependent sunburn protective skin hyperpigmentation (2017)|
Journal of Investigative Dermatology|
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t yr p ho s t in i nd uced in hi bi t ion of p 2 1 obcr ab tyrosine kinase activity induces k562 to differentiate (2017)|
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