Researcher interests: We use a variety of methods including evolutionary and biophysical modeling, computer simulations and bioinformatics to research fundamental biological questions. We study self-incompatibility in plant fertilization and general principles underlying the evolution and organization of gene regulatory networks. “Self-incompatibility” is a general name for molecular mechanisms, plants have developed to avoid self-fertilization, which might lead to the spread of deleterious mutations. Research of this system addresses fundamental evolutionary questions and has practical implications on crop fertilization
Contact Business Development: Ilya Pittel

Selected Publications

transcriptional crosstalk varies between regulatory strategies (2018)| bioRxiv| Read more
barton, Tamar Friedlander, gasper tkacik, Roshan Prizak
evolution of new regulatory functions on biophysically realistic fitness landscapes (2017)| Nature Communications| Read more
barton, calin guet, Tamar Friedlander, gasper tkacik, Roshan Prizak
intrinsic limits to gene regulation by global crosstalk (2017)| Bulletin of the American Physical Society| Read more
barton, calin guet, Tamar Friedlander, gasper tkacik, Roshan Prizak
intrinsic limits to gene regulation by global crosstalk (2016)| Nature Communications| Read more
avraham mayo, Tamar Friedlander, Tsvi Tlusty, uri alon
evolution of bow tie architectures in biology (2015)| PLOS Computational Biology| Read more
avraham mayo, Tamar Friedlander, Tsvi Tlusty, uri alon
mutation rules and the evolution of sparseness and modularity in biological systems (2013)| PLOS ONE| Read more
asaf tal, donald court, Tamar Friedlander, joel stavans, nina costantino, rinat arbelgoren, shiri meshner
effects of post transcriptional regulation on phenotypic noise in escherichia coli (2013)| Nucleic Acids Research| Read more
Tamar Friedlander, naama brenner
adaptive response and enlargement of dynamic range (2011)| Mathematical Biosciences and Engineering| Read more
Tamar Friedlander, naama brenner
adaptive response by state dependent inactivation (2009)| Proceedings of the National Academy of Sciences of the United States of America| Read more
Tamar Friedlander, naama brenner
cellular properties and population asymptotics in the population balance equation (2008)| Physical Review Letters| Read more

Contact for more information:

Ilya Pittel
VP, BD AGTECH, FOODTECH, VETERINARY & ENVIRONMENT
+972-2-6586693
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