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Prof. Yechezkel Barenholz

Researcher interests: liposomes , Relationship between physical and biological properties of biological membranes. Characterization of viral membranes. Relationship between lipid composition of cell membranes to membrane and cell functions. Involvement of lipids in the aging p
FACULTY / SCHOOL: School of Medicine - IMRIC
Contact Business Development: Keren-Or Amar
All projects by researcher: Ayana Pharma | Nano-mupirocin for injection | Ceramide-based Liposomal Drug for the Treatment of Multi-Drug Resistant Cancer | a Novel pre-treatment for the Prevention of Allergic reactions to medicines using a drug-free Carriers | Novel computational method for identification of Drug Candidates for Liposomal Reformulation | Novel Drug Delivery System of Large Molecules for Localized Sustained Release | Repurposed Drugs for COVID-19 Treatment
Nanotechnology (20)Drugs (12)Liposomes (1)Doxil (1)

Selected Publications

Yechezkel Barenholz, dalit landesmanmilo, dan peer, kavita thakur, leoni a kunzschughart, manu smriti singh, meir goldsmith, sushmita chatterjee, tally levy
ovarian spheroid based tumor models represent vascularized tumors and enables the investigation of nanomedicine therapeutics (2020)| Nanoscale| Read more
Ahuva Cern, Yechezkel Barenholz, eva medina, manfred rohde, mathias muesken, oliver goldmann, william j weiss
liposomal mupirocin holds promise for systemic treatment of invasive staphylococcus aureus infections (2019)| Journal of Controlled Release| Read more
asaf shemesh, Yechezkel Barenholz, lior shaltiel, Uri Raviv, yael levikalisman
synthesis and characterization of thiolate protected gold nanoparticles of controlled diameter (2019)| Journal of Physical Chemistry C| Read more
Yechezkel Barenholz, erik orfi, gergely tibor kozma, ildiko vashegyi, Janos Szebeni, laszlo dezsi, laszlo rosivall, rudolf urbanics, tamas fulop, tamas meszaros, tom eirik mollnes, yaelle bavli
pseudo anaphylaxisto polyethylene glycol peg coatedliposomes roles of anti peg igm and complement activation in a porcinemodel of human infusion reactions (2019)| ACS Nano| Read more
Yechezkel Barenholz, eliahu kalmanzon, eliahu zlotkin
liposomes as a model system to study shark repellency (2019)| | Read more
Yechezkel Barenholz, bing mae chen, ilan winkler, Janos Szebeni, rivka cohen, steve r roffler, yaelle bavli
doxebo doxorubicin free doxil like liposomes is safe to use as a pre treatment to prevent infusion reactions to pegylated nanodrugs (2019)| Journal of Controlled Release| Read more
abbi abdelrehim, Yechezkel Barenholz, ling zhang, lior shaltiel, lynda k harris, stephen high
the use of tail anchored protein chimeras to enhance liposomal cargo delivery (2019)| PLOS ONE| Read more
Yechezkel Barenholz, keren turjeman, m elbaz, m rabie, moria gross, n yanay, yaelle bavli, yoram nevo
liposomal steroid nano drug is superior to steroids as is in mdx mouse model of duchenne muscular dystrophy (2019)| Nanomedicine: Nanotechnology, Biology and Medicine| Read more
Yechezkel Barenholz, gergely tibor kozma, Janos Szebeni, keren turjeman, koga miyahara, rudolf urbanics, tamas meszaros, taro shimizu, tatsuhiro ishida
involvement of complement activation in the pulmonary vasoactivity of polystyrene nanoparticles in pigs unique surface properties underlying alternative pathway activation and instant opsonization (2018)| International Journal of Nanomedicine| Read more
Yechezkel Barenholz, dima shamrakov, einat nativroth, oren regev, sioma nudelman, sivan peretzdamari, xiaohui wei
cardinal role of intraliposome doxorubicin sulfate nanorod crystal in doxil properties and performance (2018)| ACS Omega| Read more
Ahuva Cern, alexander tropsha, Yechezkel Barenholz, David Marcus, Amiram Goldblum
new drug candidates for liposomal delivery identified by computer modeling of liposomes remote loading and leakage (2017)| Journal of Controlled Release| Read more
Ahuva Cern, allon e moses, ayelet michaelgayego, Yechezkel Barenholz, erez koren, Amiram Goldblum, yaelle bavli, yan q xiong
nano mupirocin enabling the parenteral activity of mupirocin (2016)| European Journal of Nanomedicine| Read more
Yechezkel Barenholz, dganit danino, hadas perlstein, peter gimeson, rivka cohen, Abraham Rubinstein, tanya turovsky
thermotropic behavior of celecoxib loaded beta casein micelles relevance to the improved bioavailability (2015)| European Journal of Nanomedicine| Read more
Ahuva Cern, Yechezkel Barenholz, einat nativroth, Amiram Goldblum
effect of solubilizing agents on mupirocin loading into and release from pegylated nanoliposomes (2014)| Journal of Pharmaceutical Sciences| Read more
Ahuva Cern, alexander tropsha, Yechezkel Barenholz, Amiram Goldblum
computer aided design of liposomal drugs in silico prediction and experimental validation of drug candidates for liposomal remote loading (2014)| Journal of Controlled Release| Read more

Success Stories & related Product & PR

DOXIL (Caeylx)

DOXIL is indicated for the treatment of patients with ovarian cancer whose disease has progressed or recurred after platinum-based chemotherapy.

Product developed by:
Prof. Yechezkal Barenholz, Faculty of Medicine, Hebrew University & Prof....
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Contact for more information:

Keren-Or Amar
VP, Business Development, Healthcare
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