Researcher interests: liposomes , Relationship between physical and biological properties of biological membranes. Characterization of viral membranes. Relationship between lipid composition of cell membranes to membrane and cell functions. Involvement of lipids in the aging process. Application of liposomes in biomedical problems.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Biochemistry and Molecular Biology
Selected Publications
new drug candidates for liposomal delivery identified by computer modeling of liposomes remote loading and leakage (2017)|
Journal of Controlled Release|
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lipid assemblies and uses thereof and some ph and electrostatic modulating lipids to be used in said assemblies (2016)|
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nano mupirocin enabling the parenteral activity of mupirocin (2016)|
European Journal of Nanomedicine|
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thermotropic behavior of celecoxib loaded beta casein micelles relevance to the improved bioavailability (2015)|
European Journal of Nanomedicine|
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effect of solubilizing agents on mupirocin loading into and release from pegylated nanoliposomes (2014)|
Journal of Pharmaceutical Sciences|
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computer aided design of liposomal drugs in silico prediction and experimental validation of drug candidates for liposomal remote loading (2014)|
Journal of Controlled Release|
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the antioxidant tempamine in vitro antitumor and neuroprotective effects and optimization of liposomal encapsulation and release ()|
Langmuir|
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characterization of pegylated nanoliposomes co remotely loaded with topotecan and vincristine relating structure and pharmacokinetics to therapeutic efficacy ()|
Journal of Controlled Release|
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nano drugs based on nano sterically stabilized liposomes for the treatment of inflammatory neurodegenerative diseases ()|
PLOS ONE|
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therapeutic efficacy of combined pegylated liposomal doxorubicin and radiofrequency ablation comparing single and combined therapy in young and old mice ()|
Journal of Controlled Release|
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Success Stories & related Product & PR
DOXIL (Caeylx)
DOXIL is indicated for the treatment of patients with ovarian cancer whose disease has progressed or recurred after platinum-based chemotherapy.
Product developed by:
Prof. Yechezkal Barenholz, Faculty of Medicine, Hebrew University & Prof....
Product developed by:
Prof. Yechezkal Barenholz, Faculty of Medicine, Hebrew University & Prof....
