Researcher interests: liposomes , Relationship between physical and biological properties of biological membranes. Characterization of viral membranes. Relationship between lipid composition of cell membranes to membrane and cell functions. Involvement of lipids in the aging process. Application of liposomes in biomedical problems.
FACULTY / SCHOOL: School of Medicine - IMRIC
DEPARTMENT: Biochemistry and Molecular Biology
Selected Publications
ovarian spheroid based tumor models represent vascularized tumors and enables the investigation of nanomedicine therapeutics (2020)|
Nanoscale|
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liposomal mupirocin holds promise for systemic treatment of invasive staphylococcus aureus infections (2019)|
Journal of Controlled Release|
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synthesis and characterization of thiolate protected gold nanoparticles of controlled diameter (2019)|
Journal of Physical Chemistry C|
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pseudo anaphylaxisto polyethylene glycol peg coatedliposomes roles of anti peg igm and complement activation in a porcinemodel of human infusion reactions (2019)|
ACS Nano|
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liposomes as a model system to study shark repellency (2019)|
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doxebo doxorubicin free doxil like liposomes is safe to use as a pre treatment to prevent infusion reactions to pegylated nanodrugs (2019)|
Journal of Controlled Release|
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the use of tail anchored protein chimeras to enhance liposomal cargo delivery (2019)|
PLOS ONE|
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liposomal steroid nano drug is superior to steroids as is in mdx mouse model of duchenne muscular dystrophy (2019)|
Nanomedicine: Nanotechnology, Biology and Medicine|
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involvement of complement activation in the pulmonary vasoactivity of polystyrene nanoparticles in pigs unique surface properties underlying alternative pathway activation and instant opsonization (2018)|
International Journal of Nanomedicine|
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cardinal role of intraliposome doxorubicin sulfate nanorod crystal in doxil properties and performance (2018)|
ACS Omega|
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new drug candidates for liposomal delivery identified by computer modeling of liposomes remote loading and leakage (2017)|
Journal of Controlled Release|
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nano mupirocin enabling the parenteral activity of mupirocin (2016)|
European Journal of Nanomedicine|
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thermotropic behavior of celecoxib loaded beta casein micelles relevance to the improved bioavailability (2015)|
European Journal of Nanomedicine|
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effect of solubilizing agents on mupirocin loading into and release from pegylated nanoliposomes (2014)|
Journal of Pharmaceutical Sciences|
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computer aided design of liposomal drugs in silico prediction and experimental validation of drug candidates for liposomal remote loading (2014)|
Journal of Controlled Release|
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Success Stories & related Product & PR
DOXIL (Caeylx)
DOXIL is indicated for the treatment of patients with ovarian cancer whose disease has progressed or recurred after platinum-based chemotherapy.
Product developed by:
Prof. Yechezkal Barenholz, Faculty of Medicine, Hebrew University & Prof....
Product developed by:
Prof. Yechezkal Barenholz, Faculty of Medicine, Hebrew University & Prof....
