Researcher interests: Peptides, synthesis, biology and conformation. Conversion of peptides into drugs. Tyrosine kinase inhibitors as antiproliferative drugs.
FACULTY / SCHOOL: Faculty of Science

Selected Publications

agata gitlindomagalska, Chaim Gilon, israel alshanski, johnny n naoum, mattan hurevich, moshe bentolila
diffusion enhanced amide bond formation on a solid support (2019)| Organic Process Research & Development| Read more
berta levavisivan, Chaim Gilon, ishwar atre, ishwar s parhar, naama mizrahi, satoshi ogawa
deciphering direct and indirect effects of neurokinin b and gnrh in the brain pituitary axis of tilapia (2019)| Frontiers in Endocrinology| Read more
adi schumacherklinger, gabriel nussbaum, Chaim Gilon, Amnon Hoffman, shira dishon
myristoylation confers oral bioavailability and improves the bioactivity of c myd 4 4 a cyclic peptide inhibitor of myd88 (2019)| Molecular Pharmaceutics| Read more
gerard marx, Chaim Gilon
molecular basis of neural memory definingthe engram (2018)| Research in Medical & Engineering Sciences| Read more
adi schumacher, alaa talhami, dimitrios karussis, gabriel nussbaum, Chaim Gilon, Amnon Hoffman, ibrahim kassis, joseph fanous, shira dishon
development of a novel backbone cyclic peptide inhibitor of the innate immune tlr il1r signaling protein myd88 (2018)| Scientific Reports| Read more
adi schumacherklinger, andreas f b rader, florian reichart, Chaim Gilon, Amnon Hoffman, horst kessler, michael weinmuller, shira merzbach
orally active peptides is there a magic bullet (2018)| Angewandte Chemie| Read more
adi schumacherklinger, andreas f b rader, florian reichart, Chaim Gilon, Amnon Hoffman, horst kessler, michael weinmuller, shira merzbach
oral aktive peptide gibt es ein patentrezept (2018)| Angewandte Chemie| Read more
agata gitlindomagalska, dolev zamir, Chaim Gilon, israel alshanski, mattan hurevich, moshe bentolila, salim joubran, shir zorsky
enhancing the efficiency of the solid phase peptide synthesis spps process by high shear mixing (2018)| Organic Process Research & Development| Read more
adi schumacherklinger, agata gitlindomaglaska, andreas f b rader, florian reichart, Chaim Gilon, Amnon Hoffman, horst kessler, joseph fanous, michael weinmueller, shira merzbach
enhancing oral bioavailability of cyclic rgd hexa peptides by the lipophilic prodrug charge masking approach redirection of peptide intestinal permeability from paracellular to transcellular pathway (2018)| Molecular Pharmaceutics| Read more
Chaim Gilon, nir qvit, samuel j s rubin, yftah talgan
conversion of protein active regions into peptidomimetic therapeutic leads using backbone cyclization and cycloscan how to do it yourself (2018)| Current Topics in Medicinal Chemistry| Read more
Chaim Gilon, israel alshanski, moshe bentolila, roberto novoa
optimization of chemical processes by the hydrodynamic simulation method hsm (2018)| ChemEngineering| Read more
adi schumacher, andreas f b rader, ettore novellino, florian rechenmacher, florian reichart, francesco saverio di leva, Chaim Gilon, Amnon Hoffman, horst kessler, jose m munozfelix, joseph fanous, kairbaan hodivaladilke, luciana marinelli, michael weinmuller, tobias g kapp, udaya kiran marelli
overcoming the lack of oral availability of cyclic hexapeptides design of a selective and orally available ligand for the integrin αvβ3 (2017)| Angewandte Chemie| Read more
deborah e shalev, Assaf FRIEDLER, Chaim Gilon, koushik chandra, Abraham Loyter, r benny gerber, tapta kanchan roy
a tandem in situ peptide cyclization through trifluoroacetic acid cleavage (2014)| Angewandte Chemie| Read more
deborah e shalev, Assaf FRIEDLER, Chaim Gilon, koushik chandra, Abraham Loyter, r benny gerber, tapta kanchan roy
frontispiece a tandem in situ peptide cyclization through trifluoroacetic acid cleavage (2014)| Angewandte Chemie| Read more
Aviad Levin, deborah e shalev, Assaf FRIEDLER, Chaim Gilon, Zvi Hayouka, Abraham Loyter, mattan hurevich
a comparative study of backbone versus side chain peptide cyclization application for hiv 1 integrase inhibitors (2012)| Bioorganic & Medicinal Chemistry| Read more

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