Researcher interests: Peptides, synthesis, biology and conformation. Conversion of peptides into drugs. Tyrosine kinase inhibitors as antiproliferative drugs.
FACULTY / SCHOOL: Faculty of Science

Selected Publications

adi schumacherklinger, Chaim Gilon, Amnon Hoffman, Gabriel Nussbaum, shira dishon
myristoylation confers oral bioavailability and improves the bioactivity of c myd 4 4 a cyclic peptide inhibitor of myd88 (2019)| Molecular Pharmaceutics| Read more
adi schumacher, alaa talhami, dimitrios karussis, Chaim Gilon, Amnon Hoffman, ibrahim kassis, joseph fanous, Gabriel Nussbaum, shira dishon
development of a novel backbone cyclic peptide inhibitor of the innate immune tlr il1r signaling protein myd88 (2018)| Scientific Reports| Read more
gerard marx, Chaim Gilon
the molecular basis of neural memory part 8 case studies of neuro mimetic technologies (2018)| Research in Medical & Engineering Sciences| Read more
adi schumacherklinger, andreas rader, florian reichart, Chaim Gilon, Amnon Hoffman, horst kessler, michael weinmuller, shira merzbach
oral aktive peptide gibt es ein patentrezept (2018)| Angewandte Chemie| Read more
adi schumacherklinger, andreas rader, florian reichart, Chaim Gilon, Amnon Hoffman, horst kessler, michael weinmuller, shira merzbach
orally active peptides is there a magic bullet (2018)| Angewandte Chemie| Read more
agata gitlindomagalska, dolev zamir, Chaim Gilon, israel alshanski, mattan hurevich, moshe bentolila, salim joubran, shir zorsky
enhancing the efficiency of the solid phase peptide synthesis spps process by high shear mixing (2018)| Organic Process Research & Development| Read more
adi schumacherklinger, agata gitlindomaglaska, andreas rader, florian reichart, Chaim Gilon, Amnon Hoffman, horst kessler, joseph fanous, michael weinmueller, shira merzbach
enhancing oral bioavailability of cyclic rgd hexa peptides by the lipophilic prodrug charge masking approach redirection of peptide intestinal permeability from paracellular to transcellular pathway (2018)| Molecular Pharmaceutics| Read more
Chaim Gilon, nir qvit, samuel rubin, yftah talgan
conversion of protein active regions into peptidomimetic therapeutic leads using backbone cyclization and cycloscan how to do it yourself (2018)| Current Topics in Medicinal Chemistry| Read more
Chaim Gilon, israel alshanski, moshe bentolila, roberto novoa
optimization of chemical processes by the hydrodynamic simulation method hsm (2018)| ChemEngineering| Read more
gerard marx, Chaim Gilon
the molecular basis of neural memory part 8 reviewing neuro mimetic technologies (2018)| Neuroscience and Biomedical Engineering| Read more
berta levavisivan, Chaim Gilon, Berta Levavi-Sivan
antagonistas da neurocinina b na reproducao de peixes (2018)| | Read more
evgeniy mervinetsky, gerard marx, Chaim Gilon, israel alshanski, karussis dimitrios, kiran tadi, mattan hurevich, panayiota petrou, Shlomo Yitzchaik
oxytocin monolayer based impedimetric biosensor for zinc and copper ions (2017)| ACS Omega| Read more
adi schumacher, andreas rader, ettore novellino, florian rechenmacher, florian reichart, francesco saverio leva, Chaim Gilon, Amnon Hoffman, horst kessler, jose munozfelix, joseph fanous, kairbaan hodivaladilke, luciana marinelli, michael weinmuller, tobias kapp, udaya kiran marelli
overcoming the lack of oral availability of cyclic hexapeptides design of a selective and orally available ligand for the integrin αvβ3 (2017)| Angewandte Chemie| Read more
backbone cyclized inhibitory peptides of myeloid differentiation factor 88 myd88 (2017)| | Read more
berta levavisivan, Chaim Gilon, Berta Levavi-Sivan
antagonists of neurokinin b in fish reproduction (2017)| | Read more
benny gerber, deborah shalev, Assaf FRIEDLER, Chaim Gilon, koushik chandra, Abraham Loyter, tapta kanchan roy
frontispiece a tandem in situ peptide cyclization through trifluoroacetic acid cleavage (2014)| Angewandte Chemie| Read more
benny gerber, deborah shalev, Assaf FRIEDLER, Chaim Gilon, koushik chandra, Abraham Loyter, tapta kanchan roy
a tandem in situ peptide cyclization through trifluoroacetic acid cleavage (2014)| Angewandte Chemie| Read more
Aviad Levin, deborah shalev, Assaf FRIEDLER, Chaim Gilon, Zvi Hayouka, Abraham Loyter, mattan hurevich
a comparative study of backbone versus side chain peptide cyclization application for hiv 1 integrase inhibitors (2012)| Bioorganic & Medicinal Chemistry| Read more

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